血液粘度の日内変動からみた脳梗塞及び心筋梗塞の発症機序に関する検討-1-若年男性における飲酒及び温泉浴の血液粘度の日内変動に及ぼす影響

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We have pointed out that the incidence of cerebral and myocardial infarction that occur early in the morning is high and estimated its correlation with blood viscosity as a cause. To clarify the mechanism of onset of such diseases early in the morning in further details, we examined the effect of alcohol drinking and hot spring bathing on the circadian changes in blood viscosity on normotensive and nonsmoking young men. It was observed that both drinking a bottle or 633ml of beer containing 4.5% alcohol and taking a hot spring bath at 42°C for 10 minutes at 8p.m. tended to enhance the rate of increase in blood viscosity between 4a.m. and 8a.m. the next morning as compared with the control. In contrast, drinking 500ml of water at 0a.m. after either drinking a bottle of beer or having a hot spring bath mitigated the change in blood viscosity the next morning. These findings may suggest that both drinking alcohol and taking a hot spring bath around dinner time elevate the rate of increase in blood viscosity in the next morning, leading to possible onset of cerebral and myocardial infarction. Drinking two glasses of water at midnight is effective in preventing such change in blood viscosity in the morning.
一般社団法人日本温泉気候物理医学会の論文