Structural Studies of Tryptophan Metabolites by X-ray Diffraction Method. III. The Crystal and Molecular Structure of 5-Methoxyindole-3-acetic Acid

スポンサーリンク

概要

• 論文の詳細を見る

• The crystal structure of 5-methoxyindole-3-acetic acid (5-MIAA) has been solved by application of the direct method with symbolic addition procedure. 5-MIAA, colorless transparent prism, is monoclinic, space group C2/c, with lattice parameters: <I>a</I>=34.461(9) Å, <I>b</I>=6.150(5) Å, <I>c</I>=9.480(5) Å, β=96.14(2)°, <I>Z</I>=8. The molecules are hydrogen-bonded into dimers related by the center of symmetry, which are held together in an infinite double-layered sheet structure perpendicular to the <I>a</I>-axis with N–H···O hydrogen bond between indole nitrogen and carboxyl oxygen atoms. The methyl groups of adjacent molecules contact to each other by van der Waals forces. The conformation of the side-chain is quite distinguishable from that of indole-3-acetic acid. The dihedral angle between carboxyl and indole planes is 59.5° in this molecule, whereas that is 90.0° in indole-3-acetic acid, and the carboxyl group sticks out to be perpendicular to the indole plane.

• 公益社団法人 日本化学会の論文

著者

• Fujiwara Takaji

  Faculty Of Pharmaceutical Sciences Of Osaka University

• TOMITA Ken-ichi

  Faculty of Pharmaceutical Sciences of Osaka University

• Wakahara Akio

  Faculty of Pharmaceutical Sciences, Osaka University

• Sakaki Toshimasa

  Faculty of Pharmaceutical Sciences, Osaka University

関連論文

• Crystal Structure of Serratia Protease, a Zinc-Dependent Proteinase from Serratia sp. E-15, Containing a β-Sheet Coil Motif at 2.0 Å Resolution^1
• Aurantionone, a Potent Antioxidant and Synergist from Penicillium aurantio-virens
• X-Ray Diffraction Studies of Polyhedral Inclusion Bodies of Nuclear and Cyto-Plasmic Polyhedrosis Viruses
• Structural studies of the interaction between indole derivatives and biologically important aromatic compounds. IV. The crystal and molecular structure of tryptamine:adenin-9-ylacetic acid(1:1)hemihydrate complex.
• The crystal and molecular structure of N-(thioacetyl)tryptamine. A radioprotective indole compound.
• Crystal and Molecular Structure of ω-Amino Acids, ω-Amino Sulfonic Acids and Their Derivatives. II. The Crystal and Molecular Structure of α-Form of 3-Aminopropane Sulfonic Acid, Homotaurine
• Structure of a potent antithyroid drug, 6-propyl-2-thiouracil.
• The interaction between .ALPHA.-helical poly-L-lysine and thyroxine as measured by circular dichroism.
• Crystal and Molecular Structure of ω-Amino Acids, ω-Aminosulfonic Acids and Their Derivatives. V. Crystal and Molecular Structure of γ-Guanidino Propane Sulfonic Acid
• Crystal and molecular structure of mitomycin C, an anticancer antibiotic.
• The crystal and molecular structure of zinc complex of 2-chlorobenzoic acid. I. The crystal and molecular structure of bis(2-chlorobenzoato)zinc(II).
• Crystal and Molecular Structure of ω-Amino Acids, ω-Amino-Sulfonic Acids and Their Derivatives. VII. The Crystal and Molecular Structure of DL-Carnitine Hydrochloride
• Crystal and Molecular Structure of ω-Amino Acids, ω-Aminosulfonic Acids and Their Derivatives. VI. The Crystal and Molecular Structure of DL-γ-Amino-β-hydroxybiityric Acid (GABOB), A Nervous Inhibitory Chemical Transmitter
• The crystal and molecular structure of zinc complex of 2-chlorobenzoic acid. II. The crystal and molecular structure of .MU.3-hydroxo-tri-.MU.-(2-chlorobenzoato)dizinc(II) dihydrate.
• Structural Studies of Tryptophan Metabolites by X-ray Diffraction Method. I. The Crystal and Molecular Structure of 5-Hydroxy-DL-Tryptophan
• Crystal and Molecular Structure of ω-Amino Acids, ω-Aminosulfonic Acids and Their Derivatives. I. The Crystal and Molecular Structure of γ-Guanidinobutyric Acid Hydrochloride and Hydrobromide
• Crystal and Molecular Structure of ω-Amino Acids, ω-Amino Sulfonic Acids and Their Derivatives. IV. The Crystal and Molecular Structure of γ-Aminobutyric Acid (GABA), a Nervous Inhibitory Transmitter
• The Crystal and Molecular Structure of Tyramine Hydrochloride
• Structural Studies of Tryptophan Metabolites by X-ray Diffraction Method. II. The Crystal and Molecular Structure of Tryptamine Hydrochloride
• Structural studies of the interaction between indole derivatives and biologically important aromatic compounds. II. The crystal and molecular structure of the tryptamine-phenylacetic acid (1:1) complex.
• Molecular conformations of .GAMMA.-aminobutyric acid and .GAMMA.-amino-.BETA.-hydroxybutyric acid in aqueous solution.
• Structural Studies of Tryptophan Metabolites by X-ray Diffraction Method. III. The Crystal and Molecular Structure of 5-Methoxyindole-3-acetic Acid
• Structural studies of the interaction between indole derivatives and biologically important aromatic compounds. I. The crystal and molecular structure of the indole-3-acetic acid-nicotinamide (1:1) complex.
• Crystal and molecular structure of .OMEGA.-amino acids, .OMEGA.-aminosulfonic acids and their derivatives. IX. Crystal and molecular structure of 3-amino-2-hydroxy-1-propanesulfonic acid.
• Crystal and Molecular Structure of ω-Amino Acids, ω-Aminosulfonic Acids and Their Derivatives. III. The Crystal and Molecular Structure of γ-Guanidino-β-hydroxypropane Sulfonic Acid
• The Crystal Structure of 1-Ethyl-5-bromouracil. I. The Crystal Structure of the Form I Crystal of 1-Ethyl-5-bromouracil

もっと見る 閉じる

スポンサーリンク