Structural studies of the interaction between indole derivatives and biologically important aromatic compounds. IV. The crystal and molecular structure of tryptamine:adenin-9-ylacetic acid(1:1)hemihydrate complex.

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概要

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• The crystal structure of tryptamine: adenin-9-ylacetic acid (1 : 1) hemihydrate complex has been determined by the X-ray method. The crystal is monoclinic, space group P2<SUB>1</SUB>/c with unit-cell dimensions: <I>a</I>=9.164(2), <I>b</I>=6.908(1), <I>c</I>=29.524(4) Å and β=110.98(2)°. The structure was solved by application of MULTAN and refined by the block-diagonal least-squares method to give a final <I>R</I>-value of 0.064. No specific interaction between indole and adenine rings is observed. Both component molecules are held together by three-dimensional frameworks of hydrogen bonds around a twofold screw axis to form an infinite helical array along the b-direction. Two kinds of dimer formation around a center of symmetry are observed between adenin-9-ylacetic acid molecules.

• 公益社団法人 日本化学会の論文

著者

• INOUE Masatoshi

  Osaka Gastric Cancer Chemotherapy Group, Second Department of Surgery, Osaka University Medical Scho

• Ishida Toshimasa

  Osaka Univ. Of Pharmaceutical Sciences

• TOMITA Ken-ichi

  Faculty of Pharmaceutical Sciences of Osaka University

• Senda Susumu

  Osaka College of Pharmacy

• Ishida Toshimasa

  Osaka College of Pharmacy

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