Annonamine, a New Aporphine Alkaloid from the Leaves of Annona muricata
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概要
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Atypical Parkinsonism in the Caribbean Island Guadeloupe is thought to be associated with the consumption of plants of the Annonaceae family, especially Annona muricata (soursop). In this study, a new aporphine alkaloid named annonamine (1) was isolated from the leaves of A. muricata L. together with four known benzylisoquinoline alkaloids (2—5). The structures of the isolated compounds were elucidated by the spectroscopic method.
- 公益社団法人 日本薬学会の論文
著者
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Otsuka Hideaki
Department Of Pharmacognosy Graduate School Biomedical Sciences Hiroshima University
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Takeda Yoshio
Faculty Of General Arts And Sciences The Tokushima University
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Matsunami Katsuyoshi
Department Of Pharmacognosy Graduate School Biomedical Sciences Hiroshima University
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Ohta Shigeru
Department Of Bioorganic And Medicinal Chemistry Faculty Of Pharmaceutical Sciences University Of To
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Kotake Yaichiro
Department of Xenobiotic Metabolism and Molecular Toxicology, Graduate School of Biomedical Sciences, Hiroshima University
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Matsushige Ayano
Department of Xenobiotic Metabolism and Molecular Toxicology, Graduate School of Biomedical Sciences, Hiroshima University
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Ohta Shigeru
Department of Xenobiotic Metabolism and Molecular Toxicology, Graduate School of Biomedical Sciences, Hiroshima University
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