日本人の耳硬化症

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The incidence of otosclerosis in Japanese is low and only a few authors have reported temporal bone findings in otosclerosis.In our experience, six surgically acquired specimens from ears with typical audiometric characteristics of stapes fixation revealed foci which belonged to a classification of a true otosclerosis.The specimens showed all stages of otosclerotic maturation:i) osteoclastic destruction and osteoblastic activities around the newly forming bone.ii) osteoid blue bone with osteoblasts, forming the “blue mantle”.iii) acidphilic remodeling bone with osteoblasts.iv) highly mineralized acidphilic bones with a mosaic-like appearance.In most of stapes fixation in tissues from Japanese patients, the same otosclerosis as is seen in Caucasians was evident.
耳鼻咽喉科臨床学会の論文

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