聴力変動によるメニエ-ル病の蝸電図所見の変化 (内藤儁教授退官記念論文集)

概要

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Electrocochleographic changes accompanying fluctuations in hearing loss on 4 patients with Meniere's disease were reported. Extratympanic electrocochleography (ECochG) was performed again after the audiogram had changed at one or more frequencies. The intervals between these ECochGs ranged from 1 month to 2 years. In two patients whose audiogram had changed only at one frequency, no significant change in ECochG was found. In two patients whose audiogram had changed at three frequencies, changes in action potential (AP) thresholds corresponded to changes in the audiograms. Negative summating potential (-SP) detection thresholds and -SP amplitudes remained unchanged, but -SP/AP ratios were significantly changed. In one of two patients with significant changes in ECochG N1 latency was prolonged accompanying progression of the hearing loss. The mechanism causing changes in ECochG accompanying fluctuations in hearing loss was discussed.
耳鼻咽喉科臨床学会の論文