鼻アレルギ-におけるヒスタミン固定能の推移--とくにヒスタグロビン局所噴霧吸入療法のヒスタミン固定能に対する効果を中心として

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Histaminopexic power (H. P. P) was measured in 102 patients with nasal allergy before and after treatment and the following aspects were evaluated.Method of treatment: hyposensitization treatment, subcutaneous injection of histaglobin, aerosol nebulized vapor of histaglobin and inhalation of beclomethasone.Determination of H. P. P.: made according to the formalin-treated hemagglutination inhibition test (Sakano).(1) The pretreatment H. P. P. was not more than 256 times in 64% (65 patients) of the patients. House dust and rag weed produced low titers in the majority of the patients, where as Japanese cedar gave high titers. Furthermore, low titers were seen in the majority of the patients having the complex of the above-mentioned three antigens with respect to antigens other than these three, there was such a tendency that the larger the number of antigens involved, the higher the titer.(2) As for the transition of the histaminopexic power in the patients of nasal allergy who received treatment, it was either constantly maintained or markedly increased if hyposensitization treatment and histaglobin treatment were given, whereas no constant tendency was seen when beclomethasone inhalation was given. A rapid increase of the histaminopexic power was observed when aerosol nebulized vapor of histaglobin was given in proportion to the interval of medication and frequencies of medication.(3) The result suggests that there is some correlation between the histaminopexic power and the clinical effect.
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鼻アレルギ-におけるヒスタミン固定能の推移--とくにヒスタグロビン局所噴霧吸入療法のヒスタミン固定能に対する効果を中心として

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