Histochemical Studies on Molony Sarcoma Virus-Induced Osteosarcoma in Rats
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For induction of experimental bone tumor, newborn Wistar-King-Aptekman or wistar-Lewis rats were received the intraperitoneal injection of the virus suspension.The samples from the induced bone tumors were examined by histochemical procedures on mucopolysaccharides, nucleic acid, lipid, non-specific alkaline phosphatase and acid phosphatase. The tumor cytoplasm showed the intensive activity of alkaline phosphatase. Lipid contents and glycogen were scanty.The histochemical findings of the induced tumor in rats were almost similar to that of osteoblastic type of human osteosarcoma.
- 西日本整形・災害外科学会の論文
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