Clinicopathological study of peripheral nervous tumors.

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We performed clinicopathological study of peripheral nervous tumors with limbs and trunks at our clinic.Of twenty-three patients, 14 patients were men and nine woman. The sex ratio was slightly skewed toward man with 14:9. In regared to the location, the tumors were found predominantly in the lower extremity.Tumors occurred as either a solitary lesion (12 cases) or multiple lesions (11 cases). Twelve solitary lesions showed histological diagnosis such as a solitary schwannoma (8 cases), neurofibroma (1 case) and malignant schwannoma (3 cases) respectively. On the other hand, 11 cases with the multiple lesions were diagnosed histologically as neurofibromatosis in association with von Recklinghausen's disease.In the solitary lesions, eight schwannomas and one neurofibroma were easily extirpated, and have been followed with no recurrence. In three malignant schwannomas, one case died of the disease. In the multiple lesions, surgical extirpation was performed for benign each tumor, and no recurrence has been found in three cases. Of 11 of von Recklinghausen's disease, three cases (27%), of which two died of the disease, showed malignant transformation. Therefore, they were considered as poor in prognosis.
西日本整形・災害外科学会の論文