人より分離したナイアシン陰性抗酸菌の一例

概要

論文の詳細を見る
This paper is to report biochemical properties of a strain of mycobacterium isolated from a patient who has been treated as human tuberculosis. The patient has been administered with streptomycin and PAS since 1951. The mycobacteria were isolated 13 times of 18 times cultivations since 1965, and the number of colonies obtained in each positive cultivation was approximately more than 100. No other different types of mycobacteria were obtained. The most important property of this strain was negative in Niacin test. O ther properties of the strain were as follows: 1) The strain requires ap p roximately 2 weeks for colony formation on the Ogawa-medium and needs glycerin for growth. Optimal temperature for growth is 37°C, and no growth is observed at 30°C as well as 40°C. 2) The colony is R-type with light yellow-white color, and no changes in the color are seen in dark and in light. The cord formation in liquid medium is demonstrated. 3) Urease and nicotinamidase reaction are positive, but benzamid a se and formamidase are negative. 4) The strain is sensitive to INH but resistant to streptomycin, Kanamycin and PAS. 5) When the bacilli were inoculated intramuscularly into a guinea-pig, no path o genic changes were observed in the spleen, but tubercle-like-findings were noted in the pancreas. 6) Tuberculin reactions of the patient were observed by injection of human tubercle bacillus-tuberculin but not by nonphotochromogen and other mycobacterial tuberculin. From the results described above, the possibility of this strain bein g human tubercle bacillus can be excluded, but there still remain some problems in order to determine whether this strain is any kind of atypical mycobacteria or not.
日本結核病学会の論文

人より分離したナイアシン陰性抗酸菌の一例

スポンサーリンク

概要

著者

関連論文

スポンサーリンク