細胞・抗酸菌感染系に関する研究-3-

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Comparisons of the phagocytosis of Myc, lepraemurium by various kinds of established cells and the effees of the enzyme and detergent which were used for isolating the bacilli from infected tissues on the phagocytosis of Myc, lepraemurium were studied and the following results were obtained.<BR>1. Myc. lepraemurium were phagocytosed by the HeLa, MS, FL, S, as well as L cells at the same rates.<BR>2. Trypsin treatment which was used for isolating and purifying the bacilli reduced the phagocytosis rates. On the contrary, desoxycholate treatment significantly stimulated the phagocytosis rates of Myc, lepraemurium.<BR>3. It was demonstrated that heat treatment of the bacilli (caused) the enhancement of the phagocytosis of Myc, Lepraemurium. It is probably presumed that the mechanism of stimulation of phagocytosis by desoxycholate and heat treatment is due to the changes in ionic charge of the cell surface of Myc, lepraemurium.
日本細菌学会の論文