THE EFFECT OF VITAMIN D3 AND DIETARY CALCIUM LEVEL ON THE CADMIUM-INDUCED MORPHOLOGICAL AND BIOCHEMICAL CHANGES IN RAT INTESTINAL MUCOSA
スポンサーリンク
概要
- 論文の詳細を見る
The effect of vitamin D3 and dietary calcium level on the cadmium-induced changes was observed in the duodena of rats raised on various diets differing in vitamin D and calcium levels. Observation with scanning electron microscopy revealed that vitamin D and dietary calcium were required for normal intestinal villi and microvilli formation. The damaged cells were observed in the intestinall villi of cadmium-exposed rats. The length of microvilli was shortened in the cadmium-exposed rats. Furthermore, dietary cadmium reduced the enzyme activities in microvilli. Especially, alkaline phosphatase activity was reduced in the cadmium-exposed groups, even though it was still responsive to vitamin D3. These effects with cadmium were modulated by vitamin D3 and dietary calcium level. That is, in the presence of vitamin D3 and calcium, the effect of cadmium on intestinal villi and microvilli was reduced.
- 財団法人 学会誌刊行センターの論文
著者
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野田 節子
東海大 医
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細谷 憲政
Department of Nutrition, School of Health Sciences, Faculty of Medicine, University of Tokyo
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吉沢 節子
Department of Nutrition, School of Health Sciences, Faculty of Medicine, University of Tokyo
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森内 幸子
Department of Nutrition, School of Health Sciences, Faculty of Medicine, University of Tokyo
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野田 節子
Department of Anatomy, Tokyo Womens Medical College
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久保田 くら
Department of Anatomy, Tokyo Womens Medical College
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山田 和彦
Department of Nutrition, School of Health Sciences Faculty of Medicine, University of Tokyo
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森内 幸子
Department of Food and Nutrition, Faculty of Home Economics, Japan Women's University
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森内 幸子
Department of Nutrition, School of Health Sciences Faculty of Medicine, University of Tokyo
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吉沢 節子
Department of Nutrition, School of Health Sciences Faculty of Medicine, University of Tokyo
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細谷 憲政
Department fo Nutrition, School of Health Sciences, Faculty of Medicine, University of Tokyo
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細谷 憲政
Department of Nutrition, School of Health Sciences Faculty of Medicine, University of Tokyo
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野田 節子
Department of Anatomy, Tokyo Women's Medical College
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久保田 くら
Department of Anatomy, Tokyo Women's Medical College
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山田 和彦
Department fo Nutrition, School of Health Sciences, Faculty of Medicine, University of Tokyo
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