Effect of pyridoxal 5'-phosphate on the 1,25-dihydroxyvitamin D3 receptor system.
スポンサーリンク
概要
- 論文の詳細を見る
The effect of pyridoxal 5'-phosphate on the 1, 25-dihydroxyvitamin D3 receptor system has been studied by using pig intestinal chromatin. Pyridoxal 5'-phosphate did not affect the binding of 1, 25-dihydroxyvitamin D3 to its receptor extracted from chromatin with hypertonic KCI, although in the presence of pyridoxal 5'-phosphate 1, 25-dihydroxyvitamin D3-receptor complexes were not readily precipitated with polyethylene glycol. In contrast, pyridoxal 5'-phosphate showed a potency to dissociate the 1, 25-dihydroxyvitamin D3 receptor from chromatin in a dose-dependent manner. A low concentration of pyridoxal 5'phosphate was as effective as hypertonic KCl in dissociating the receptor from chromatin, while pyridoxine, p-nitrophenyl phosphate, or inorganic phosphate was much less effective. These observations suggest the inhibitory effect of pyridoxal 5'-phosphate on the recognition of 1, 25-dihydroxyvitamin D3 by its receptor system.
- 財団法人 学会誌刊行センターの論文
著者
-
渡部 誠
Department of Nutrition, School of Health Sciences, Faculty of Medicine, University of Tokyo
-
志村 二三夫
Department of Nutrition, School of Health Sciences, Faculty of Medicine, University of Tokyo
-
志村 純子
Department of Nutrition, School of Health Sciences, Faculty of Medicine, University of Tokyo
-
細谷 憲政
Department fo Nutrition, School of Health Sciences, Faculty of Medicine, University of Tokyo
関連論文
- 病者用食品におけるビタミンB_1補給の意義(ビタミン学の原点・栄養学への21世紀的回帰「サプリメントを考える」,日本ビタミン学会第59回大会)
- 2-II-4 オタマジャクシ血漿Retinol-binding proteinに及ぼすチロキシン投与の影響について(日本ビタミン学会 : 第30回大会一般研究発表要旨)
- 5. 1,25-(OH)_2-D_3リセプター(R_D)に対するピリドキサールリン酸(PLP)の作用(第219回会議研究発表要旨,脂溶性ビタミン総合研究委員会)
- 1-II-14 ブタ小腸粘膜の1,25-(OH)_2-D_3受容体 : 第35回大会一般研究発表要旨 : 日本ビタミン学会
- ブタ小腸粘膜クロマチンの非占有型1,25-dihydroxyvitamin D3受容体〔英文〕
- 2005年 日本人の食事摂取基準における銅の摂取基準の設定について
- 治療用特殊食品及びこれらを使用した治療食の微量ミネラル含有量の検討
- A New Aspect on the Mechanism of Intestinal Cholesterol Absorption in Rat
- EFFECT OF VARIOUS SUGARS ON THE INDUCTION OF CHICK EMBRYONIC INTESTINAL DISACCHARIDASES IN THE ORGAN CULTURE SYSTEM
- THE EFFECT OF 1, 25-DIHYDROXYCHOLECALCIFEROL ON THE MULTIPLE FORMS OF ALKALINE PHOSPHATASE AND THE SIALIC ACID INCORPORATION INTO MICROSOMES OF CHICK DUODENUM
- Property and Physiological Role of Biliary Secretory IgA in Rats
- VITAMIN D3 EFFECT ON THE CALCIUM CONTENT IN SUBCELLULAR FRACTIONS OF RAT INTESTINAL MUCOSA
- INHIBITORY EFFECT OF CADMIUM ON VITAMIN D STIMULATED CALCIUM TRANSPORT IN RAT DUODENUM IN VITRO
- THE EFFECT OF VITAMIN D3 AND DIETARY CALCIUM LEVEL ON THE CADMIUM-INDUCED MORPHOLOGICAL AND BIOCHEMICAL CHANGES IN RAT INTESTINAL MUCOSA
- VISUALIZATION OF VITAMIN D-DEPENDENT CALCIUM BINDING PROTEIN IN CHICK INTESTINAL TISSUE BY IMMUNO-SCANNING ELECTRON MICROSCOPY
- Effect of Sucrose and Acarbose Feeding on the Development of Streptozotocin-Induced Diabetes in the Rat
- Biliary Immunoglobulins in Protein-Energy Malnourished Rats
- Calcium-Binding Proteins in Bovine Milk: Calcium-Binding Properties and Amino Acid Composition
- Calmodulin-Like Fanction of Calcium-Binding Protein in Bovine Milk
- CHANGES OF IMMUNOREACTIVE SUCRASE-ISOMALTASE COMPLEX IN RAT SMALL INTESTINE DURING POSTNATAL DEVELOPMENT AND MATURATION ALONG THE VILLUS-CRYPT AXIS
- EFFECT OF FOOD RESTRICTION ON INTESTINAL DISACCHARIDASES IN STREPTOZOTOCIN-INDUCED DIABETES OF RAT
- SOME CHARACTERISTICS OF EARLY APPEARING ISOMALTASE IN INTESTINAL MUCOSA OF SUCKLING RAT
- DEVELOPMENTAL CHANGES IN THE SUCRASE-ISOMALTASE COMPLEX IN RAT INTESTINAL MUCOSA
- EFFECT OF EXOGENOUS THYROXINE ON PLASMA RETINOL-BINDING PROTEIN OF TADPOLE (RANA CATESBEIANA) WITH SPECIAL REFERENCE TO AFFINITY FOR HUMAN PREALBUMIN
- EFFECT OF EXOGENOUS POLYUNSATURATED FATTY ACIDS ON LIPOGENIC ENZYME ACTIVITY IN RAT LIVER UNDER FIXED CARBOHYDRATE CONSUMPTION
- CHARACTERIZATION OF STEROL CARRIER PROTEIN BINDING WITH 7-DEHYDROCHOLESTEROL AND VITAMIN D3
- BINDING OF 7-DEHYDROCHOLESTEROL TO STEROL CARRIER PROTEIN AND VITAMIN D3 EFFECT
- THE EFFECT OF 1α-HYDROXYVITAMIN D3 AND CORTISONE ON THE DEVELOPMENT OF CHICK DUODENAL ALKALINE PHOSPHATASE IN ORGAN CULTURE
- PROTEINS OF CHICK DUODENAL BRUSH BORDERS DURING DEVELOPMENTAL CHANGES
- Demonstration of Sucrase-Isomaltase Complex in Chick Intestine
- Effect of aging and castration on the changes in the levels of bone .GAMMA.-carboxyglutamic acid-containing protein in bone and serum of female rat.
- Purification and characterization of calciumbinding protein containing .GAMMA.-carboxyglutamic acid from rat bone.
- Biological activity of the endoperoxides derived from vitamin D derivatives by dye-sensitized photo-oxidation.
- BINDING PROTEINS FOR 1, 25-DIHYDROXYCHOLE-CARCIFEROL AND 25-HYDROXY-CHOLECARCIFEROL
- Competence of 1.ALPHA.,25-dihydroxyvitamin D3 receptor system in embryonic chick intestine.
- Interaction of 1.ALPHA.,24-dihydroxyvitamin D3 with the chick intestinal 1.ALPHA.,25-dihydroxyvitamin D3 receptor system.
- Intestinal absorption of dinitrophenyl-lysine and effect of immunization with dinitrophenylated bovine serum albumin.
- Possible role of insulin status in the increased lipogenic enzyme activity by dietary medium-chain triglyceride in rat liver.
- Changes in glucose uptake by and phlorizin binding to brush-border membrane vesicles of small intestine from streptozotocin-induced diabetic rats.
- The effect of 1,25-dihydroxycholecalciferol on the changes of bone .GAMMA.-carboxyglutamic acid-containing protein in bone and serum of developing chick.
- Digestion and absorption of sugars and sugar substitutes in rat small intestine.
- Effect of pyridoxal 5'-phosphate on the 1,25-dihydroxyvitamin D3 receptor system.
- Changes of sugar-evoked transmural potential differences in intestine of rats with streptozotocin-induced diabetes.
- Some properties of luminal sucrase and sucrase-isomaltase complex in rat small intestine.
- Some characteristics of cytosol binding protein for 1.ALPHA.,25-dihydroxycholecalciferol and 25-hydroxycholecalciferol in rat intestinal mucosa.
- Inhibition of .BETA.-sitosterol on intestinal cholesterol absorption in rat using in vivo dual isotope ratio method.
- Regulatory effect of calcium-regulating hormones on the synthesis and/or secretion of bone .GAMMA.-carboxyglutamic acid-containing protein in chick embryonic calvaria in vitro.
- Effect of dietary vitamin D3 and cadmium on the lipid composition of rat intestinal brush border membranes.
- Hypertrophic effect of unavailable carbohydrate on cecum and colon in rats.
- Bone .GAMMA.-carboxyglutamic acid-containing protein (BGP)-induced changes in chick embryonic calvaria in vitro.
- The changes of bone .GAMMA.-carboxyglutamic acid-containing protein in bone and serum of developing chick.
- Changes of the activity and content of sucrase-isomaltase complex in the intestinal mucosa during the development of streptozotocin-induced diabetes in rats.
- Effect of dietary medium chain triglyceride on lipogenic enzyme activity in rat liver.