Changes in glucose uptake by and phlorizin binding to brush-border membrane vesicles of small intestine from streptozotocin-induced diabetic rats.
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概要
- 論文の詳細を見る
The changes in the intestinal glucose transport in strep-tozotocin-induced diabetic rats have been demonstrated with brush-border membrane vesicles. When Na+ -dependent D-glucose uptake and phlorizin binding activities were compared, both significantly increased either in the jejunum or ileum of diabetic rats compared with those of control. Kinetic studies showed the increases in the Vmax of glucose transport and the maximum binding of phlorizin (Bmax), whereas the Kt. and Kd remained unchanged, respectively. These results suggested that the increase in glucose transport in diabetic rat intestine was due to the increase in the number of the intact glucose transporters.
- 財団法人 学会誌刊行センターの論文
著者
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森内 幸子
Department of Food and Nutrition, Faculty of Home Economics, Japan Women's University
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細谷 憲政
Department fo Nutrition, School of Health Sciences, Faculty of Medicine, University of Tokyo
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山田 和彦
Department fo Nutrition, School of Health Sciences, Faculty of Medicine, University of Tokyo
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山田 和彦
Department of Nutrition, School of Health Sciences, Faculty of Medicine, University of Tokyo
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辻 義光
Department of Nutrition, School of Health Sciences, Faculty of Medicine, University of Tokyo
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高井 克治
Department of Nutrition, School of Health Sciences, Faculty of Medicine, University of Tokyo
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辻 義光
Department of Nutrition, School of Health Sciences, Faculty of Medicine, The University of Tokyo
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