Intestinal absorption of dinitrophenyl-lysine and effect of immunization with dinitrophenylated bovine serum albumin.
スポンサーリンク
概要
- 論文の詳細を見る
The intestinal absorption of dinitrophenyl-lysine (DNP-lys) was studied with a special interest on the role of the immune system in the absorption of small molecules which are recognized as nonself. [3H]-DNPlys was rapidly absorbed by ligated intestinal loops in situ via a saturable and unique route. When [3H]-DNP-lys was preincubated with the immune serum obtained from rats immunized with dinitrophenylated bovine serum albumin (DNP-BSA), the [3H]-DNP-lys absorption was depressed. The absorption of [3H]-DNP-lys in DNP-BSA-immunized rats was depressed compared to the control. The results obtained suggest that the immune system play a role in avoiding the absorption of small molecules with antigenicity.
- 財団法人 学会誌刊行センターの論文
著者
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志村 二三夫
Department of Nutrition, School of Health Sciences, Faculty of Medicine, University of Tokyo
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志村 純子
Department of Nutrition, School of Health Sciences, Faculty of Medicine, University of Tokyo
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細谷 憲政
Department fo Nutrition, School of Health Sciences, Faculty of Medicine, University of Tokyo
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志村 純子
Department of Nutrition, School of Health Sciences,Faculty of Medicine, University of Tokyo
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島崎 茂樹
Department of Nutrition, School of Health Sciences,Faculty of Medicine, University of Tokyo
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志村 二三夫
Department of Nutrition, School of Health Sciences,Faculty of Medicine, University of Tokyo
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