下顎歯肉部に初発したB細胞型非ホジキン悪性リンパ腫の1例

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Malignant lymphoma occurs rarely in the oral cavity.<BR>We experienced a case of malignant lymphoma arising from the mandibular gingiva in 69-year-old man. His chief complaint was swelling on the gingiva of the right side molar region. At first, we suspected periostitis of the mandible, so we administrated anti-biotics. We palpated fluctuation at the region and incised, but it was solid tumor and not discharged pus. Histopathological examination found chronic inflammation of gingiva. After incision, the clinical course was bad, so we performed biopsy again.<BR>Histopathological examination indicated non-Hodgkin's lymphoma, diffuse large cell type. The tumor cell demonstrated B-cell type by PAP method. The immunologic study demonstrated IgM and kappa.<BR>Patient received chemotherapy with VCR and ADM. After 3 courses of therapy, the tumor disappeared.
社団法人日本口腔外科学会の論文