口底扁平上皮癌の臨床的病理学的検討

概要

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A clinicopathological study was made of squamous cell carcinoma of the floor of the mouth treated at Department of Maxillofacial Surgery, Kobe University School of Medicine between 1980 and 1989, and the following findings were obtained. 1.There was distinct male predominance in the patients. 2.TNM classification was as follows;Ti: 26%, T2: 57%, T3: 4%, T4: 13%, and NO: 30%, N1: 26%, N2: 44%. 3.The anterior or antero-posterior portion was the most common site of carcinoma of the floor of the mouth. 4.Interstitial irradiation was performed in six patients, and local cure was obtained in all of them. 5. Two of eleven patients who underwent operation had local recurrence in soft tissue. There was no correlation between preoperative clinical or histological findings and local recurrence. 6. Histological examination revealed that level I neck was at greatestrisk of nodal metastases, and often bilateral nodes were involved. 7. Classical or modified radical neck dissection was undergone for node metastases. Out of 10 patients (15 necks) who had histologically proven neck metastases, one patient died of neck disease. 8. 5-year survival rate was 63.6% in the patients who underwent the operation, and 83.3% in those who had interstitial irradiation.
社団法人日本口腔外科学会の論文