エタノールアミンおよびそのメチル誘導体の血漿脂質に及ぼす影響

概要

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Ethanolamine and its methylderivatives (monomethylethanolamine, dimethylethanolamine and choline) were added to the semi-synthetic diet of mice (50mmol/kg diet). Their effects on plasma and liver lipids were studied. The addition of ethanolamine caused a significant decrease in plasma cholesterol level. In contrast, methylderivatives of ethanolamine showed no effect on plasma cholesterol level. A decrease in plasma triglyceride level was observed after the addition of ethanolamine, dimethylethanolamine and choline. These agents also significantly decreased the concentration of hepatic triglyceride and tended to decrease hepatic cholesterol. Monomethylethanolamine increased the relative weight of the liver and the cholesterol content. The composition and concentration of hepatic phospholipids did not significantly vary after the addition of ethanolamine and its derivatives, except for monomethylethanolamine. It is suggested that ethanolamine and its methylderivatives have different effects on plasma lipids.
社団法人日本農芸化学会の論文