A 27-Year-Old Woman Diagnosed as Polycystic Ovary Syndrome Associated with Graves Disease

概要

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Polycystic ovary syndrome (PCOS) and Graves disease are the common causes of menstrual irregularity leading to infertility in women of child-bearing age. A 21-year-old female patient visited us with complaints of oligomenorrhea and hand tremor. She was diagnosed as having PCOS and hyperthyroid Graves disease, simultaneously. She had low body weight (BMI: 16.4 kg/m2), mild hirsutism, and thyrotoxicosis. The patient was treated with anti-thyroid drug and beta-blocker for about two years, and then recovered to normal thyroid function. Although some studies have suggested a connection between PCOS and autoimmune thyroiditis, no study indicated that PCOS is associated with Graves disease until now. Here, we describe the first case report of a lean woman with normal insulin sensitivity presenting PCOS and Graves disease simultaneously.