タイトル無し

概要

論文の詳細を見る
In cases with the abnormal pancreatico-choledocho-ductal junction, the free communication between the pancreatic duct and the common bile duct is occurred. The intraductal pressure of pancreatic duct is normally higher than that of the bile duct. So, the reflux of pancreatic juice occurs into the bile duct.In this study, we found "canibalism" like carcinoma cells in the main pancreatic duct in a case of adenosquamous cell carcinoma of the gallbladder with the abnormal pancreatico-choledochoductal junction. So, the possibility of bile reflux into the pancreatic duct was also considered. But, 11 from 15 cases with the abnormal pancreatico-choledocho-ductal junction did not show remarkable changes in the pancreas histopathologically. Nevertheless, 4 cases which were considered to be associated with infection of the biliary tract such as choledochal dilatation were found to have degeneration and desquamation of the pancreatic ductal epithelia, aggregation of bacilli in the ducts and diffuse interlobular fibrosis.Therefore, we conclude that in cases with the abnormal pancreatico-choledocho-ductal junction not much remarkable changes were found in the pancreas histopathologically excluding those with biliary tract infection, even if the reflux of bile into the pancreatic duct had been occurred.
財団法人日本消化器病学会の論文