ACUTE GASTRODUODENAL LESIONS FOLLOWING HEAD INJURY AND BURN A CLINICAL STUDY OF 85 CASES

概要

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The incidence and clinical features of acute gastroduodenal lesions were studied in 63 patients with head injury and 22 with burn. The acute gastroduodenal lesions were found in high frequency of 62 out of 85 cases (72.9%) by early endoscopy. Hemorrhagic erosion was thought to be the common lesion following severe injuries. It developed within two days after injury and usually located in the corpus of the stomach. Acute gastric ulcer, on the contrary, was occurred after one week and it was usually multiple. It was suggested that sepsis had a strong correlation with the development of acute gastric ulcer.Gastrointestinal bleeding was most frequent as the initial symptom and seen in 51 of 85 cases (65.9%). Only 2 cases complained abdominal pain. The other 17 cases were asymptomatic. Medical treatment including blood transfusion was ineffective in 16 of 51 cases with gastrointestinal bleeding and its mortality was 10%. These features were thought to be quite different from those of chronic peptic ulcer and acute gastric mucosal lesions following drug ingestion or emotional stress.
財団法人日本消化器病学会の論文