:(III) The Hemoperfusion and Oxygen Insufficiency in the Gastric Mucosa after Head-or Thermal-injury Analyzed by Reflectance Spectrophotometry

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To investigate the mechanism of acute gastric mucosal lesions, the reflectance spectrophotometer system has been applied to the human gastric mucosa during gastrofiberscopy by using flexible coaxial fiber optic bundles and a computer-equipped spectrophotometer.The spectra were taken from corpus andd antral mucosa of 15 patients with thermal- or headinjury and compared with those from 7 healthy volunteers. In all patients, mucosal blood volume decreased to various degrees after thermal- or head-injury. In seven cases in which mucosal blood volume decreased to about 30% of the level of healthy volunteers, the acute gastric mucosal lesions appeared mainly in the corpus mucosa in three days after the measurement of mucosal blood volume. Although the blood volume in the antral mucosa also decreased to the almost same level as that of the corpus mucosa, the lesions did not appear in the antral mucosa.In conclusion, analysis of mucosal blood flow after thermal-or head-injury by reflectance spectrophotometry revealed that ischemia in the gastric mucosa is the main cause of the acute gastric mucosal lesions in the patients with thermal-or head-injury.
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