ULTRASONICALLY GUIDED PERCUTANEOUS FINE NEEDLE ASPIRATION BIOPSY OF THE PANCREAS:II. Clinical Significance in the differential diagnosis of chronic pancreatitis and pancreatic cancer

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Ultrasonically guided percutaneous fine needle aspiration biopsy for cytological diagnosis was performed on twenty-two patients with pancreatic lesions of ultrasonically scanned solid mass.Final diagnosis of these patients was pancreatic cancer in eighteen patients and chronic pancreatitis in four patients. In the three patients with pancreaetic cancer, radiation therapy had been performed before aspiration biopsy by this procedure because these three patints were diagnosed by other clinical methods.In thirteen of the fifteen patients with pancreatic cancer, except for three patients with pancreatic cancer for which radiation therapy had been performed, malignant cells were aspirated.In the remaining two patients with pancreatic cancer, however, the aspiration specimens were inadequate, being not enough for establishing cytological diagnosis. In four patients of chronic pancreatitis, normal pancreatic cells were aspirated, successfully ruling out the pancreatic cancer.Those results demonstrated that the high diagnostic accuracy (89%, 17/19) was obtained in the pancreatic tumor by this procedure. Of the fifteen pancreatic cancers, the accuracy was 87% (13/15); there was no false positive in the four chronic pancreatitis (100%, 4/4).This method, the combination of ultrasonic scanning and percutaneous fine needle aspiration biopsy, may be considered as very useful for diagnosis of the pancreatic tumor, especially for differential diagnosis of chronic pancreatitis and pancreatic cancer.
財団法人日本消化器病学会の論文

ULTRASONICALLY GUIDED PERCUTANEOUS FINE NEEDLE ASPIRATION BIOPSY OF THE PANCREAS:II. Clinical Significance in the differential diagnosis of chronic pancreatitis and pancreatic cancer

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