飽和脂肪酸のクロルホスホン化反応

概要

論文の詳細を見る
Lauric acid was chlorophosphonated under the following conditions : 0.15 mol of lauric acid was dissolved in 0.3 mol of phosphorus trichloride, followed by introduction of dried oxygen into the solution with the flow rate of 70 ml/min for 3 hr. The product was distilled under vucuum after treating with methanol. The distillation residue was then fractionated by silica gel column chromatography, obtaining phosphorus-containing product.<BR>This product was confirmed as monophosphonolauric acid by means of elementary analysis and potentiometric titration.<BR>From the result of NMR and IR spectroscopic analysis of the product in comparison with the spectra of the synthesized α-phosphonolauric acid, it was confirmed that the chlorophosphonation occured on carbons other than α- and terminal carbons in the alkyl chain.<BR>In the case of the chlorophosphonation of methyl laurate, the yield of phosphonolauric acid was slightly higher than in the case of lauric acid. The properties of the product from methyl laurate were the same with those from lauric acid.
日本油化学会の論文