日本人の赤血球および血漿中 Glutathione Peroxidase 活性

概要

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Glutathione peroxidase (GPX) activities in human erythrocyte and plasma were determined by a modified form of Paglias method. In erythrocytes, the mean (±SE) GPX activity in men was 59.7 (± 1.17) and in women 60.9 (±1.33). There was no significant variation with regard to sex, but positive correlation was observed between GPX activity and age. The regression line gave GPX activity=0.127×age+54.3(r=0.29, p<0.01). For plasma, the mean (±SE) GPX activity in men was 5.35 (±0.143) and in women 5.84 (±0.163). The mean for women was therefore higher at a significance of p<0.05. In terms of age, in women plasma activity was highest in the 30-59 age range and lowest in the 60 to 89 age range. The erythrocyte to plasma GPX activity ratio gave 11.7 (±0.465) for men and 11.3 (±0.510) for women, with the ratio for women in the 30-39 age group significantly lower and those for higher age groups in both sexes significantly higher than the remainder. There was thus no correlation between erythocyte and plasmas GPX activity.
日本衛生学会の論文