ラットにおける食物繊維の食用タール色素障害阻止効果

概要

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Recently, it has been reported that the intake of fiber constituents can prevent chronic diseases including ishemic heart disease and diabetes. In this experiment, the inhibitory effects of fiber contained in rice bran were demonstrated when tar dyes were given to rats.The results were as follows:1) The fibrous contents of rice bran included 15.8% hemicellulose, 7.4% cellulose, and 4% lignin.2) For 18 months, rats were fed a diet containing 5% of one of 11 the tar dyes or one containing 5% the dye and 5% of rice bran fiber. The survival rate at the end of the test was much greater for the latter group.3) Comparisons of weight gains during the first 4 weeks following the start of the experiment revealed that the group given only the tar dye was markedly retarted in growth, while the group given both the fiber and the dye had normal growth.4) Comparisons of tumor development during the test period disclosed abdominal lymphosarcoma in two rats among the dye only group. Both rats survived until the end of the test, but no tumor development at all was observed in the dye + fiber group.
日本衛生学会の論文