Chromatin Transcription by Progestogen-Receptor Complex in Rabbit Uterus
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概要
- 論文の詳細を見る
This study was designed to investigate the chromatin transcription <I>in vitro</I> by progesterone-receptor complex in the estrogen-primed rabbit uterus. RNA synthesis by the uterine chromatin was stimulated when progesterone-uterine cytosol complex was bound to the chromatin and the stimulation was dependent upon the dose of the bound progesterone-cytosol 8S complex and upon the incubation time of the complex in the presence of the chromatin. Either norethindrone-or dydrogesteroneuterine cytosol complex also stimulated the uterine chromatin transcription but the extent was less than that of progesterone complex. These results indicate that progesterone as well as synthetic progestogens can directly regulate chromatin tran scription via progesterone receptor in the rabbit uterine cells.
- 社団法人 日本内分泌学会の論文
著者
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TSURUSAKI Toshihide
Department of Obstetrics and Gynecology Kyoto Prefectural University of Medicine
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Okada Hiroji
Department Of Obstetrics And Gynecology Kyoto Prefectural University Of Medicine
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Tamaya Teruhiko
Departmen T Of Obstetrics And Gynecology Kyoto Prefectural University Of Medicine
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Tamaya T
Departmen T Of Obstetrics And Gynecology Kyoto Prefectural University Of Medicine
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Ide Norimasa
Department Of Obstetrics And Gynecology Kyoto Prefectural University Of Medicine
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FURUTA NORIO
Department of Obstetrics and Gynecology, Kyoto Prefectural University of Medicine
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OHONO YOUSUKE
Department of Obstetrics and Gynecology, Kyoto Prefectural University of Medicine
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TSURUSAKI TOSHIHIDE
Department of Obstetrics and Gynecology, Kyoto Prefectural University of Medicine
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