Changes in Sex Hormones and Calcium Regulating Hormones with Reference to Bone Mass Associated with Aging
スポンサーリンク
概要
- 論文の詳細を見る
Measurement of bone mineral content (BMC), intestinal <SUP>47</SUP>Ca absorption, and calcium regulating hormones and sex steroids in serum were performed on 32 healthy aged subjects and 26 control young subjects. In BMC, there was a progressive fall after age 40, with the rate of decrease being greater in women than in men. A significant correlation was observed between BMC and testosterone in the men and between estrogens and BMC in the women, suggesting the possible importance of testosterone in men and estrogens in women in maintaining bone mass. Plasma PTH showed no change with age. However, the reserve capacity of the parathyroid was significantly reduced in the aged women. Serum levels of ionized calcium were low in aged subjects, indicating a possible alteration with age in the feedback control between ionized calcium levels and parathyroid hormone secretion. C-cell funtion was also decreased with age. Plasma 1, 25-(OH) <SUB>2</SUB>D and <SUP>47</SUP>Ca absorption tended to decrease with age. Age-related bone loss could be a reflection of the interaction of these hormonal imbalance occurring with age.
- 社団法人 日本内分泌学会の論文
著者
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TORIZUKA KANJI
Department of Nuclear, Medicine Kyoto University School of Medicine
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MORITA Rikushi
Shiga University of Medical Science
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Konishi Junji
Department Of Nuclear Medicine And Diagnostic Imaging Graduate School Of Medicine Kyoto University
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Morita Rikushi
Department Of Neurosurgery Kinki University Medical School
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Yamamoto Itsuo
Department Of Radiology Shiga University Of Medical Science
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Fukunaga Masao
Department Of Geriatric Medicine Graduate School Of Medicine The University Of Tokyo
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Aso Takeshi
Department Of Comprehensive Reproductive Medicine Graduate School Tokyo Medical And Dental Universit
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DOKOH SHIGEHARU
Department of Nuclear Medicine and Radiology, Kyoto University School of Medicine
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KOUSAKA TADAKO
Department of Nuclear Medicine and Radiology, Kyoto University School of Medicine
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NAKAJIMA KOTOKO
Department of Nuclear Medicine and Radiology, Kyoto University School of Medicine
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MOTOHASHI TORU
Department of Obsterics and Gynecology, Kyoto University School of Medicine
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Torizuka Kanji
Department Of Nuclear Faculty Of Medicine Kyoto University
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KONISHI JUNJI
Department of Nuclear Medicine and Radiology, Kyoto University School of Medicine
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YAMAMOTO ITSUO
Department of Nuclear Medicine and Radiology, Kyoto University School of Medicine
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FUKUNAGA MASAO
Department of Nuclear Medicine and Radiology, Kyoto University School of Medicine
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TORIZUKA KANJI
Department of Nuclear Medicine and Radiology, Kyoto University School of Medicine
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