クエン酸の熱分解ガスクロマトグラフィーおよびその分析的応用
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The gas chromatographic analysis of polybasic carboxylic acids has been performed usually by their methyl esters or trimethyl silyl derivatives. To simplify this time consuming procedure, authors tried to apply the pyrolysis gas chromatographic technique. The pyrolysis of polybasic carboxylic acids in flush heater chamber of a gas chromatograph would give the corresponding acid anhydrides, with which the determination of the original acids can be carried out. The present paper deals with the case of citric acid and the application to the determination of citric acid in Migrainine (antipyrine-caffeine citrate).<BR>The main pyrolyzates of the citric acid were identified as citraconic anhydride and itaconic anhydride. An overlapped peak of these two pyrolyzates was used for the determination of citric acid in commercial Migrainine.<BR>The analytical results showed a good agreement with those of titrimetric method.
- 社団法人 日本分析化学会の論文
著者
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- 奨励賞受賞 萩中 淳氏の業績
- 第二のルネサンス
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- 界面活性剤の分析 (II) : 親油性基の分析 (その3) ガスクロマトグラフィー以外の方法を用いる分析
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- クエン酸の熱分解ガスクロマトグラフィーおよびその分析的応用