HEMORRHAGE AND FIBRINOLYSIS
スポンサーリンク
概要
- 論文の詳細を見る
The influence of increased fibrinolysis on bleeding tendency was studied. In acute leukemia and aplastic anemia, the co-existence of high fibrinolytic activity and thrombocytopenia was frequently observed in hemorrhagic cases. In fibrinolytic state, the bleeding tendency was more prominent in thrombocytopenic animals. In microscopic studies of mesenteric vessels of the rabbits, no bleeding was found even after activation of fibrinolysis or thrombocytopenia was induced. When the small vessels were previously injured with mechanical or chemical stimuli, a massive hemorrhage ensued. It is concluded therefore that vascular injury is an important factor in the mechanisms of hemorrhage even in elevated fibrinolytic state and that thrombocytopenia enhances the fibrinolytic bleeding.
- The Keio Journal of Medicineの論文
著者
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ANDO Yasuhiko
Department of Blood Transfusion Service Center Tokai University Hospital
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Tsukada Toshiyasu
Department Of Hematology Toranomon Hospital
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Sugita Hiroshi
Department Of Materials Science Graduate School Of Science And Technology Kobe University
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Shirakura Noriyuki
Department Of Mechanical Engineering Kyusyu Institute Of Technology
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Okubo Hiroshi
Department Of Aerospace Engineering Osaka Prefecture University
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MATSUKI YASUO
Department of Internal Medicine, School of Medicine, Keio University
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HASEGAWA MITSUTO
Department of Internal Medicine
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SHIRAKURA NORIYUKI
Department of Medicine, School of Medicine, Keio University Tokyo
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OZAWA SHINJIRO
Department of Medicine, School of Medicine, Keio University Tokyo
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SAKURAI HIDEYA
Department of Medicine, School of Medicine, Keio University Tokyo
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OZAWA SHINJIRO
Department of Internal Medicine, School of Medicine Keio University
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MATSUKI YASUO
Department of Medicine, School of Medicine, Keio University Tokyo
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MATSUKI YASUO
Department of Internal Medicine, School of Medicine, Kcio University
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OKUBO HIROSHI
Department of Medicine, School of Medicine, Keio University Tokyo
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