Analyses of Developmental Ability of (BALB/c × C57BL/6) F<SUB>1</SUB> and ICR Mouse Embryos Fertilized <I>In Vitro</I> and Their Chromosome at the First Cleavage Division
スポンサーリンク
概要
- 論文の詳細を見る
Superovulated eggs in (BALB/c×C57BL/6) F<SUB>1</SUB> and ICR (outbred in a closed colony) female mice were fertilized <I>in vitro</I> with spermatozoa obtained from caudal epididymides of ICR males. Air-dried chromosome preparations were made from colcemid-primed 1-cell eggs and stained by the C-banding method. The fertilization rate was lower in F<SUB>1</SUB> eggs than in ICR eggs (88 vs. 92%, P<0.02). The incidence of metaphase ("syngamy") eggs was higher in F<SUB>1</SUB> eggs, and the incidence of pronuclear and late prometaphase ("pre-syngamy") eggs was higher in ICR eggs (P<0.001, P<0.005), showing delayed progress of the first cleavage in the ICR eggs. Developmental rates from 2-cell to 4-cell stage and from morula to blastocyst stage were significantly lower in ICR eggs (P<0.001) than in F<SUB>1</SUB> eggs. These results show that a delay of embryo development had already appeared before male and female genomes fused (pre-syngamy). The incidence of triploidy, which might be caused by dispermy, was higher in F<SUB>1</SUB> eggs, in both the pronuclear and mitotic stages (P<0.001). A little aneuploidy and structural aberration of chromosomes occurred in both F<SUB>1</SUB> and ICR eggs, and no significant difference was observed between F<SUB>1</SUB> and ICR eggs. The sex ratio at the first cleavage stage in both F<SUB>1</SUB> and ICR eggs showed no significant deviation from equality.
著者
-
Yoshizawa Midori
United Graduate School Of Agriculture Tokyo University Of Agriculture And Technology
-
Yoshizawa Midori
Department Of Animal Breeding And Reproduction Faculty Of Agriculture Utsunomiya University
-
Nakamoto Satoshi
Department Of Electrical And Electronic Engineering Kobe University
-
Okamoto Akira
Department Of Biochemistry Meikai University School Of Dentistry
-
Muramatsu Takashi
Department Of Biochemistry
-
TAKADA Masaru
Department of Animal Breeding and Reproduction, Faculty of Agriculture Utsunomiya University
-
OKAMOTO Akira
Department of Animal Breeding and Reproduction, Faculty of Agriculture Utsunomiya University
-
YOSHIZAWA Midori
Department of Animal Breeding and Reproduction, Faculty of Agriculture Utsunomiya University
-
MURAMATSU Takashi
Department of Animal Breeding and Reproduction, Faculty of Agriculture Utsunomiya University
-
NAKAMOTO Satoshi
Department of Animal Breeding and Reproduction, Faculty of Agriculture Utsunomiya University
関連論文
- Phylogenetic implications of Jungle Crow Corvus macrorhynchos and Carrion Crow Corvus corone based on base sequence of mitochondrial DNA
- Blastocyst Production from In Vitro-produced Day-2 Bovine Embryos Classified by Cleavage Stage, and Cytogenetical Evaluation of the Resultant Day-8 Blastocysts
- Biological characteristics of the junctional epithelium
- PII-27 Immunohistological studies on the palatine rugae development in mice
- The expression and localization of osteopontin in the mouse major salivary glands
- The odontoblast as a sensory receptor cell? The expression of TRPV1 (VR-1) channels
- Microarray Analysis on Odontogenesis-related-genes in Mouse Dental Papillae(International Symposium of Maxillofacial and Oral Regenerative Biology in Okayama 2005)
- Immunohistochemical Localization of Pleiotrophin and Midkine in the Lingual Epithelium of the Adult Rat
- CHANGES IN ACTIVITIES OF DAILY LIVING,PHYSICAL FITNESS, AND DEPRESSIVE SYMPTOMS AFTER SIX-MONTH PERIODIC WELL-ROUNDED EXERCISE PROGRAMS FOR OLDER ADULTS LIVING IN NURSING HOMES OR SPECIAL NURSING FACILITIES
- Uric Acid and Left Ventricular Hypertrophy in Japanese Men
- Receptor-type protein tyrosine phosphatase ζ as a component of the signaling receptor complex for midkine-dependent survival of embryonic neurons
- Preoperative serum midkine concentration is a prognostic marker for esophageal squamous cell carcinoma
- Frequent Expression of Midkine Gene in Esophageal Cancer Suggests a Potential Usage of Its Promoter for Suicide Gene Therapy
- Evaluation of the Surface Roughness of Compomer by Laser Scanning Microscopy
- Evaluation of the surface roughness of Compomer by Laser Scanning Microscope
- Study of the Fluoridated Adhesive Resin Cement : Fluoride Release, Fluoride Uptake and Acid Resistance of Tooth Structures
- WDX Study of Resin-dentin Interface on Wet vs.Dry Dentin
- Expression Profile and Localization of Mouse Calcitonin (CT) Sense/Antisense Transcripts in Pre- and Postnatal Tissue Development
- DIFFERENTIAL EXPRESSION OF mRNA FOR α2, 3-SIALYLTRANSFERASE DURING DEVELOPMENT OF RAT RETINA
- PJ-525 The Acute and Late Outcome of Sirolimus-eluting Stent(SES) in Small Coronary Arteries Comparing with Bare-Metal Stent(BMS)(Coronary revascularization, PCI-19 (IHD) PJ88,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the
- PJ-519 Late Outcome of Drug Eluting Stent (DES) in the High Restenosis Factors in Bare Metal Stent (BMS) Era(Coronary revascularization, PCI-18 (IHD) PJ87,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation
- PJ-358 8 Month-outcome of Very Long (>36mm) Silolimus-eluting-stent Implanted Segments(Coronary revascularization, PCI-16 (IHD) PJ61,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- OE-083 Midkine Ameliorates Ischemia/Reperfusion Injury of Cardiac Muscle through a Reduction of Apoptotic Reaction(Myocardial Ischemia-Reperfusion, Basic and Clinical 1 (IHD) : OE10)(Oral Presentation (English))
- Phylogenetic Analysis of Bacillus cereus Isolates from Severe Systemic Infections Using Multilocus Sequence Typing Scheme
- Human N-Acetylglucosamine-6-O-Sulfotransferase Involved in the Biosynthesis of 6-Sulfo Sialy Lewis X : Molecular Cioning, Chromosomal Mapping, and Expreeion in Various Organs and Tumor Cells
- Clusters of Basic Amino Acids in Midkine: Roles in Neurite-Promoting Activity and Plasminogen Activator-Enhancing Activity^1
- Le^X Structure Enhances Myocardial Differentiation from Embryonic Stem Cells
- Enzyme-Linked Immunoassay for Midkine, and Its Application to Evaluation of Midkine Levels in Developing Mouse Brain and Sera from Patients with Hepatocellular Carcinomas
- PJ-518 Acute and Late Outcome of Sirolimus Eluting Stent in Bifurcation Lesions Comparing with Bare Metal Stent(Coronary revascularization, PCI-18 (IHD) PJ87,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulat
- The Blastocyst Production Rate and Incidence of Chromosomal Abnormalities by Developmental Stage in In Vitro Produced Porcine Embryos
- Overexpression of Midkine in Pancreatic Duct Adenocarcinomas Induced by N-Nitrosobis(2-oxopropyl)amine in Hamsters and Their Cell Lines
- Expression of Syndecan-1 and -3 during Embryogenesis of the Central Nervous System in Relation to Binding with Midkine^1
- Midkine Expression is Associated with Postnatal Development of the Lungs
- Distinct expression of midkine and pleiotrophin in the spinal cord and placental tissues during early mouse development
- Embigin/basigin subgroup of the immunoglobulin superfamily : Different modes of expression during mouse embryogenesis and correlated expression with carbohydrate antigenic markers
- Restricted Expression of Xenopus Midkine Gene during Early Development
- PE-409 High-density Lipoprotein Cholesterol as a Biomarker to Predict Risk for Myocardial Infarction in Working Population(PE069,Preventive Medicine/Epidemiology/Education 2 (H),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese C
- OE-069 Adiponectin as a Potential Biomarker to Predict Risk for Myocardial Infarction in Male Working Population(OE12,ACS/AMI (Clinical/Pathophysiology) (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Socie
- PJ-760 Obesity as a Major Risk Factor for Acute Myocardial Infarction in Japanese working age(Acute myocardial infarction, clinical(diagnosis / treatment)(12)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Soc
- A Novel Truncated Variant Form of Ebk/MDK1 Receptor Tyrosine Kinase Is Expressed in Embryonic Mouse Brain
- Midkine, a Heparin-Binding Growth/Differentiation Factor, Exhibits Nerve Cell Adhesion and Guidance Activity for Neurite Outgrowth In Vitro
- Molecular Cloning and Expression of Endo-β-N-Acetylglucosaminidase D, Which Acts on the Core Structure of Complex Type Asparagine-Linked Oligosaccharides^1
- The Ratio of Splicing Variants of MGC-24/CD164, a Sialomucin, Correlates with the Metastatic Protential of Colorectal Carcinomas
- Structure of the Mouse Basigin Gene, a Unique Member of the Immunoglobulin Superfamily
- cDNA Cloning and Sequence Analysis of a Novel Calcium Binding Protein with Oligoproline Motif
- CBP-140, a Novel Endoplasmic Reticulum Resident Ca^-binding Protein with a Carboxy-terminal NDEL Sequence Showed Partial Homology with 70-kDa Heat Shock Protein (hsp70)
- Zep: A Novel Zinc Finger Protein Containing a Large Proline-Rich Domain
- PE-557 Association of Insulin Resistance with Habitual Dietary Intake of Fatty Acids among Middle-aged Japanese Men(Preventive medicine/Epidemiology/Education(04)(H),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation So
- Mutation analysis of Japanese patient with fucosidosis
- Stage-Specific Localization of Basigin, a Member of the Immunoglobulin Superfamily, During Mouse Spermatogenesis
- Effects of High Pressure Treatment on Ca^ Release and Ca^ Uptake of Sarcoplasmic Reticulum
- Pressure-induced Ca^ Release from Rabbit Sarcoplasmic Reticulum
- Midkine Counteracts the Activin Signal in Mesoderm Induction and Promotes Neural Formation^1
- Fundamental study on localized heating in hyperthermia using phase control of long-wavelength microwaves (特集 電気関係学会関西支部連合大会)
- ES細胞の糖鎖マーカー
- Thrombospondin-1 promotes fibroblast-mediated collagen gel contraction caused by activation of latent transforming growth factor β-1
- Midkine Enhances Early Stages of Collagen Gel Contraction^1
- Expression Profile of Mouse BWF1, a Protein with a BEACH Domain, WD40 Domain and FYVE Domain
- Midkine (MK) Expression in Extraembryonic Tissues, Amniotic Fluid, and Cerebrosphinal Fluid during Mouse Embryogenesis
- Mutational analysis of MECP2 in Japanese patients with atypical Rett syndrome
- Mutation analysis of two Japanese patients with Fanconi-Bickel syndrome
- Localization of Connexin 26, 32 and 43 in Rat Parotid Glands
- Increased Serum Midkine Levels during Hemodialysis Using Heparin in Chronic Renal Failure
- A method for genotyping Y chromosome-linked DYS385a and DYS385b loci
- Detection of nucleolar organizer regions on chromosomes by flourescence in situ hybridization with human 28S rRNA gene and cloning of 28S rRNA gene in Sika deer
- Analysis of Nucleolus Organizing Regions on chromosomes in Japanese Sika Deer (Cervus nippon) by fluorescence in situ hybridization using human 28S rRNA gene as a probe
- Midkine Rescues Wilms' Tumor Cells from Cisplatin-Induced Apoptosis: Regulation of Bcl-2 Expression by Midkine^1
- Expression of basigin, a member of the immunoglobulin superfamily, in the mouse central nervous system
- Transient Activation of Dihydropteridine Reductase by Ca^-activated Proteolysis(Biochemistry)
- Sexing of sika deer Cervus nippon, based on detection of SRY genes from DNA extracted from teeth
- Analyses of Developmental Ability of (BALB/c × C57BL/6) F1 and ICR Mouse Embryos Fertilized In Vitro and Their Chromosome at the First Cleavage Division
- Chromosomal Analysis of First-Cleavage Mouse Eggs Fertilized in Caffeine-Containing Medium
- Evaluation of selection media for the detection of borderline MRSA
- Midkine, a Retinoic Acid-Inducible Heparin-Binding Cytokine in Inflammatory Responses: Chemotactic Activity to Neutrophils and Association with Inflammatory Synovitis
- Midkine Inhibits apoptosis via extracellular signal regulated kinase(ERK)
- Rationale and design of the NAGOYA HEART Study : Comparison between valsartan and amlodipine regarding morbidity and mortality in patients with hypertension and glucose intolerance
- Midkine is highly expressed in neuroblastoma tissues
- Increased Midkine Gene Expression in Human Gastrointestinal Cancers
- A Splicing Factor, Prp8 : Preferential Localization in the Testis and Ovary in Adult Mice
- Syndecan-4 (Ryudocan) as a Defense Molecule in Endotoxin Shock
- Lewis X Structure Increases Cell Substratum Adhesion in L Cells^1
- A case of chronic infantile type of fucosidosis : clinical and magnetic resonance in image findings
- Molecular Cloning and Expression of a Mouse α-1,3 Fucosyltransferase Gene That Shows Homology wity the Human α-1,3 Fucosyltransferase IV Gene^1
- Role of the Carboxyl-Terminal Region in the Activity of N-Acetylglucosamine 6-O-Sulfotransferase-1
- N-Acetylglucosamine-6-O-Sulfotransferase-1 : Production in the Baculovirus System and Its Applications to the Synthesis of a Sulfated Oligosaccharide and to the Modification of Oligosaccharides in Fibrinogen
- 江上不二夫教授-複合糖質研究者の父として個人的な回想
- Vitrified-warmed ovarian tissue autotransplantation into ovariectomized mice restores sufficient ovarian function to support full-term pregnancy
- Midkine, a heparin-binding cytokine with multiple roles in development, repair and diseases
- ミッドカインのシグナル受容におけるプロテオグリカンの役割
- Midkine and Pleiotrophin: Two Related Proteins Involved in Development, Survival, Inflammation and Tumorigenesis
- Smoking and Smoking Cessation in Relation to All-Cause Mortality and Cardiovascular Events in 25,464 Healthy Male Japanese Workers
- A Retinoic Acid-Responsive Element in Human Midkine Gene
- Extended uterine receptivity for blastocyst implantation and full-term fetal development in mice with vitrified-warmed ovarian tissue autotransplantation
- The Significance of Measuring Body Fat Percentage Determined by Bioelectrical Impedance Analysis for Detecting Subjects With Cardiovascular Disease Risk Factors
- Cell Surface Glycoproteins : Biochemical, Immunological and Molecular Biological Studies
- Application of both high-performance liquid chromatography combined with tandem mass spectrometry shotgun and 2-D polyacrylamide gel electrophoresis for streptococcal exoproteins gave reliable proteomic data
- Variation in M protein production among streptococcus pyogenes strains according to emm genotype
- Detection of Methicillin-Resistant Staphylococcus aureus Using a Specific Anti-PBP2a Chicken IgY Antibody
- Expression of the Heparin-Binding Growth Factor Midkine in the Cerebrospinal Fluid of Patients with Neurological Disorders
- Essential Roles of Carbohydrate Signals in Development, Immune Response and Tissue Functions, as Revealed by Gene Targeting