Localization of Connexin 26, 32 and 43 in Rat Parotid Glands
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概要
- 論文の詳細を見る
We investigated the distribution and localization of connexin 26, 32. and 43 in rat parotid glands. Immunofluorescence microscopy revealed the presence of spots reacting for connexin 26 and 32 between endpiece cells. A few spots indicating connexin 43 occasionally were observed in the parotid glands. Connexin 43-positive spots were localized around intercalated ducts. No positive spots for these connexins were detected between ductal cells. Double immunofluorescence microscopy revealed that connexin 26-reactive sites could be observed within the same spots as connexin 32. Double immuno-electron microscopy confirmed that connexin 26 and 32 were co-localized in the same gap junction. These results suggest that connexin 26 and 32 are associated with secretory function and permeability between endpiece cells and that connexin 43 is associated with contraction of the myoepithelial cells that surround intercalated ducts in the rat parotid glands.
著者
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Lee Chan
DA UI Team. Samsung Electronics
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MURAMATSU Takashi
Department of Pathology, Tokyo Dental College
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SHIMONO Masaki
Department of Pathology, Tokyo Dental College
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Lee Chan
Department Of Chemical Engineering Korea University
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Lee Chan
Department Of Chemical And Biological Engineering Korea University
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Shimono Masaki
Department Of Pathology Oral Health Science Center Tokyo Dental College
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Shimono Masaki
Department Of Biosphere Science Faculty Of Science Toyama University
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Muramatsu Takashi
Department Of Biochemistry Nagoya University School Of Medicine
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Masaoka Takayasu
Oral Health Science Center Hrc7 Tokyo Dental College
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Muramatsu Takashi
東京歯科大学 病理学
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Muramatsu Takashi
Department Of Biochemistry
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MURAMATSU Takashi
Department of Animal Breeding and Reproduction, Faculty of Agriculture Utsunomiya University
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