EFFECTS OF MORPHINE ON THE LEVEL OF THE FREE FATTY ACIDS IN THE SERUM OF RATS
スポンサーリンク
概要
- 論文の詳細を見る
It is well known that morphine produces hyperglycemia in some laboratory animals such as rats, dogs and so on (1) by inducing the release of catecholamine from the adrenal medulla (2). As catecholamine raises the level of free fatty acids (FFA) in blood as well as that of glucose (3), there would be a possibility that morphine also raises the level of FFA in blood. On the other hand the changes of FFA in serum by the administration of morphine were reported scarcely (4, 5). The purpose of the present investigation was to examine the changes of the level of FFA in serum of the morphine-tolerant and nontolerant rats by the administration of or by the withdrawal from morphine, and was also to see whether the level of FFA in serum of the rats changed in parallel with that of glucose in blood when the rats were treated with morphine.<BR> In some cases, the content of FFA of the epididymal fat pad and the rate of lipolysis were examined in order to know the effect of morphine on the lipolysis of the adipose tissue, which is supposed to change the level of FFA in serum.
- 社団法人 日本薬理学会の論文
著者
-
MURAKI Takamura
Department of Pharmacology, Tokyo Women's Medical University, School of Medicine
-
Muraki Takamura
Department Of Pharmacology Tokyo Women's Medical College
-
MURAKI TAKAMURA
Department of Dermatology, School of Medicine, Keio University
関連論文
- Cysteinyl Leukotriene Receptor Antagonists Inhibit Tumor Metastasis by Inhibiting Capillary Permeability
- Molecular Characterization of the Mouse mtprd Gene, a Homologue of Human TPRD: Unique Gene Expression Suggesting Its Critical Role in the Pathophysiology of Down Syndrome^1
- Identification and Cloning of a Novel cDNA Belonging to Tetratricopeptide Repeat Gene Family from Down Syndrome-Critical Region 21q22.2
- Effect of S-Ethylisothiourea, a Putative Inhibitor of Inducible Nitric Oxide Synthase, on Mouse Skin Vascular Permeability
- The Effect of Acute Cold Exposure and Norepinephrine on Uncoupling Protein Gene Expression in Brown Adipose Tissue of Monosodium Glutamate-Obese Mice
- Effect of Tazarotene, an Acetylenic Retinoid, on Human Dermal Fibroblast
- EFFECTS OF MORPHINE ON THE LEVEL OF THE FREE FATTY ACIDS IN THE SERUM OF RATS
- EFFECTS OF REPEATED MORPHINE ADMINISTRATION ON COPULATION AND ON THE HYPOTHALAMIC-PITUITARY-GONADAL AXIS OF MALE RATS
- EFFECTS OF α- AND β-ADRENERGIC BLOCKERS ON CHLORPROMAZINE-INDUCED ELEVATION OF PLASMA GLUCOSE AND CYCLIC AMP IN FED MICE
- PARTIAL AGONISTIC ACTION OF MORPHINE IN THE RAT VAS DEFERENS
- EFFECTS OF MORPHINE ON THE SERUM PROLACTIN LEVELS OF MORPHINE-TOLERANT AND NONTOLERANT MALE RATS AND ON THE IN VITRO RELEASE OF PITUITARY PROLACTIN
- Effects of Morphine and Naloxone on Serum LH, FSH and Prolactin Levels and on Hypothalamic Content of LH-RF in Proestrous Rats
- INHIBITORY EFFECT OF MORPHINE ON SERUM GONADOTROPINS AND PROLACTIN OF PROESTROUS RATS
- Plasma cyclic AMP in the pethidine-dependent rat.
- Failure of morphine to affect phospholipid metabolism in superior cervical sympathetic ganglion of rats in vitro.
- DETERMINATION OF INHIBITORS OF UROKINASEACTIVATED FIBRINOLYTIC ENZYME SYSTEM BY MEANS OF GEL FILTRATION IN HUMAN SERUM
- Identification and Cloning of a Novel cDNA Belonging to Tetratricopeptide Repeat Gene Family from Down Syndrome-Critical Region 21q22.2.
- Molecular Characterization of the Mouse mtprd Gene, a Homologue of Human TPRD: Unique Gene Expression Suggesting Its Critical Role in the Pathophysiology of Down Syndromel.