Comparison of the electrocardiographic changes induced by dipyridamole infusion and treadmill exercise in patients with coronary artery disease.

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概要

• 論文の詳細を見る

• To determine whether dipyridamole infusion can be used as an alternative method to physical exercise, 87 lead body surface mapping was performed to compare the distribution patterns of ST-segment depression after 0.568mg/kg/4min dipyridamole infusion (D) and after submaximal treadmill exercise (T) in 21 patients with coronary artery disease. Significant ST-segment depression (_??_0.05mV) was observed in 19 patients after D and in 18 after T. After D and T, each patient showed a similar distribution pattern of ST-segment depression. There were no significant differences in the number of leads which showed ST-segment depression (nST: D, 15.6±11.1 vs T, 15.2±10.8) and in the maximal value of ST-segment depression (STmax: D, -0.24±0.16 vs T, -0.20±0.13mV). Good correlations were observed in nST (r=0.84) and in STmax (r=0.87) between D and T. The increase in mean pressure-rate product after T was 89%, while the increase after D was only 22%. Our results suggest that this pharmacologic test to induce myocardial ischemia may be useful in the evaluation of coronary artery disease in patients who are physically unable to perform adequate exercise.

• International Heart Journal刊行会の論文

著者

• Kubota Isao

  First Department of Internal Medicine Yamagata University School of Medicine

• Yasui Shoji

  First Deparment Of Internal Medicine Nagoya University School Of Medicine

• YASUI Shoji

  First Department of Internal Medicine, Yamagata University School of Medicine

• TSUIKI Kai

  First Department of Internal Medicine, Tohoku University School of Medicine

• IKEDA Kozue

  First Department of Internal Medicine, Yamagata University School of Medicine

• KAWASHIMA Sukehiko

  First Department of Internal Medicine, Yamagata University School of Medicine

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