Canine Model of Ventricular Fibrillation Using Programmed Stimuli and Localized Myocardial Warming or Cooling
スポンサーリンク
概要
- 論文の詳細を見る
The purpose of this study was to establish an animal model in which ventricular fibrillation (VF) can be induced reproducibly and defibrillation can be accomplished repeatedly. The left anterior descending artery (LAD) was cannulated and perfused with blood from the carotid artery in eleven openchest dogs. Electrodes of the internal defibrillator were inserted in the cavities of the left atrium and left ventricle via incisions in the left atrial appendage and left ventricular apex. The perfused blood temperature was modulated to produce regional myocardial warming (42°C) or cooling (28°C). In all dogs, VF was repeatedly induced by the combination of warming and left ventricular extrastimuli and by the combination of cooling and right ventricular extrastimuli. The VF was quickly defibrillated by use of the internal defibrillator. The mechanism of VF was found to be reentry by the analysis of activation sequences. This VF model may be useful when evaluating the efficacy of antiarrhythmic drugs because of the high reproducibility.
- Japanese Heart Journal Associationの論文
著者
-
Tomoike Hitonobu
National Cardiovascular Center
-
Kubota Isao
First Department of Internal Medicine Yamagata University School of Medicine
-
Tachibana Hidetada
First Department of Internal Medicine, Yamagata University
-
Watanabe Tetsu
First Department of Internal Medicine, Yamagata University School of Medicine
-
Yamaki Michiyasu
山形大学 循環呼吸腎臓内科学
-
Tachibana Hidetada
First Department Of Internal Medicine Yamagata University School Of Medicine
-
YAMAKI Michiyasu
First Department of Internal Medicine, Yamagata University School of Medicine, Yamagata, Japan
-
TOMOIKE Hitonobu
First Department of Internal Medicine, Yamagata University School of Medicine, Yamagata, Japan
-
Tomoike Hitonobu
First Department Of Internal Medicine Yamagata University Medical School
-
YAMAKI Michiyasu
First Department of Internal Medicine, Yamagata University School of Medicine
関連論文
- PE-364 Preliminary Report of a Multicenter Cohort Study of Myocardial Viability Assessment by Gated^Tc-Sestamibi SPECT at Rest(Nuclear cardiology-5, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- 5 A Role of Endoplasmic Reticulum Stress in the Pathophysiology of Atherosclerotic Plaques Associated with Acute Coronary Syndrome(Vulnerable Patient/Vulnerable Plaque in Acute Coronary Syndrome,Plenary Session 2 (PL-2) (H),The 73rd Annual Scientific Meet
- PJ-763 Improvement of Left Ventricular Ejection Fraction is a Predictor for Cardiac Events in Patients with Acute Myocardial Infarction(Acute myocardial infarction, clinical(diagnosis / treatment)(12)(IHD),Poster Session(Japanese),The 72nd Annual Scientif
- 5 A Role of Endoplasmic Reticulum Stress in the Pathophysiology of Atherosclerotic Plaques Associated with Acute Coronary Syndrome(Vulnerable Patient/Vulnerable Plaque in Acute Coronary Syndrome,Plenary Session 2 (PL-2) (H),The 73rd Annual Scientific Meet
- PJ-763 Improvement of Left Ventricular Ejection Fraction is a Predictor for Cardiac Events in Patients with Acute Myocardial Infarction(Acute myocardial infarction, clinical(diagnosis / treatment)(12)(IHD),Poster Session(Japanese),The 72nd Annual Scientif
- Combination of Heart-Type Fatty Acid Binding Protein and Brain Natriuretic Peptide Can Reliably Risk Stratify Patients Hospitalized for Chronic Heart Failure
- OE-183 Clinical Importance of Serum Heart-type Fatty Acid Binding Protein Levels in Heart Failure Patients : Comparisons with Sympathetic Nervous Activity(Heart Failure, Clinical 1 (M) : OE22)(Oral Presentation (English))
- OE-022 Prognostic Importance of ^I-MIBG Dynamic SPECT In Patients with Chronic Heart Failure(Nuclear Cardiology 1 (I) : OE3)(Oral Presentation (English))
- Increased Serum Levels of H-FABP in Patients with Severe Congestive Heart Failure
- ^I-MIBG Dynamic SPECT in Patients with Congestive Heart Failure
- OE-157 Clinical course and outcome of heart transplant recipients : single center' s experience at National Cardiovascular Center(Transplantation/LVAD (IHD),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Improvement of Ventricular Arrhythmia by Octreotide Treatment in Acromegalic Cardiomyopathy
- Direct Effects of Class I Antiarrhythmic Drugs on Epicardial Electrograms in Dogs
- Canine Model of Ventricular Fibrillation Using Programmed Stimuli and Localized Myocardial Warming or Cooling
- 5 A Role of Endoplasmic Reticulum Stress in the Pathophysiology of Atherosclerotic Plaques Associated with Acute Coronary Syndrome(Vulnerable Patient/Vulnerable Plaque in Acute Coronary Syndrome,Plenary Session 2 (PL-2) (H),The 73rd Annual Scientific Meet
- Direct Evidence that Sustained Dysfunction of Left Atrial Appendage Contributes to the Occurrence of Cardiogenic Brain Embolism in Patients with Paroxysmal Atrial Fibrillation
- Aortic Atherosclerosis and Abnormalities of Blood Flow Conditions Are Important as Risk Factor for Ischemic Stroke in Non-Valvular Atrial Fibrillation
- Aortic Vortex Flow Represented by Contrast Echography Is a Useful Tool to Visualize Blood Viscosity in Acute Cerebral Embolism
- Ongoing myocardial damage relates to cardiac sympathetic nervous disintegrity in patients with heart failure
- 5 A Role of Endoplasmic Reticulum Stress in the Pathophysiology of Atherosclerotic Plaques Associated with Acute Coronary Syndrome(Vulnerable Patient/Vulnerable Plaque in Acute Coronary Syndrome,Plenary Session 2 (PL-2) (H),The 73rd Annual Scientific Meet
- Functional Confirmation of Gitelman's Syndrome Mutations in Japanese
- The KCNB1/E65K Polymorphism is Not Associated With Low Prevalence of Diastolic Blood Pressure in a Japanese Population
- Leptin Gene and Leptin Receptor Gene Polymorphisms Are Associated with Sweet Preference and Obesity
- FRS-076 A link between LDL Receptor (LDLR) Gene Mutation and Clinical Manifestations in Familial Hypercholesterolemia(FRS16,Basic Mechanisms of Lipid Disorders and Metabolic Syndrome (H),Featured Research Session (English),The 73rd Annual Scientific Meeti
- PJ-898 Predicting high risk patients of coronary artery disease in heterozygous familial hypercholesterolemia from clinical features(Lipid disorders(05)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-897 A Discontinuation of LDL-apheresis Deteriorates Prognosis of Heterozygous Familial Hypercholesterolemia(FH)(Lipid disorders(05)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- 1 Evidence for Human Atrial Natriuretic Peptide and Nicorandil as an Adjunct to Reperfusion Therapy for Acute Myocardial Infarction : J-WIND Trials(Late Breaking Clinical Trials in Japan, The 71st Annual Scientific Meeting of the Japanese Circulation Soci
- 4 Abnormal Glucose Tolerance as the Risk of Progression of Heart Failure or the Onset of Coronary Heart Disease(Diabetic Cardiovascular Complications and Therapeutic Strategy, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-089 Has statin delayed the first event of coronary artery disease in heterozyhous familial hypercholesterolemia(FH)?(Lipid disorders(02)(H),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Diminution of angiotensin II-induced contraction of the abdominal aorta isolated from Watanabe heritable hyperlipidemic rabbits
- A Role for Signal Transducer and Activator of Transcription 3, Mitogen-Activated Protein Kinases, and Akt for Cardiac Phenotypes in Vivo
- Pressure and Volume Overload-Induced Cardiac Hypertrophy Is Associated with Distinct Activation of Signal Transduction Pathways
- Artial Enlargement Induced by Volume Overload Is Associated with Altenations of Wnt Signaling Proteins
- Role of Nitric Oxide in the Progression of Cardiovascular Remodeling Induced by Carotid Arterio-Venous Shunt in Rabbits
- Comparison of Nitric Oxide Production in Response to Carbachol Between Macrovascular and Microvascular Cardiac Endothelial Cells
- Chronic Hypertriglyceridemia In Watanabe Heritable Hyperlipidemic Rabbits (a model for familial combined hyperlipidaemia) Accerelates Endothelial and Medial Smooth Muscle Dysfunctions
- Does the presence of paroxysmal atrial fibrillation reflect to the atrial mechanical remodeling and the occurrence of acute ischemic stroke?
- Long-term blockade of nitric oxide synthesis attenuates volume-overload induced cardiovascular remodeling in rabbits
- Protein kinase C-Calcineurin pathway is Involved in Insulin-Like Growth Factor-1-Induced Hypertrophy of Cultured Adult Rat Ventricular Myocytes
- A novel visualization of aortic flow around the atherosclerotic plaque and possible relationship to acute ischemic stroke with sinus rhythm
- Role of Calcineurin in Insulin-Like Growth Factor-1-Induced Hypertrophy of Cultured Adult Rat Ventricular Myocytes
- Anisotropic Effects of Sodium Channel Blockers on the Wavelength for Ventricular Excitation in Dogs
- 4-Aminopyridine Inhibits the Occurrence of Ventricular Fibrillation but not Ventricular Tachycardia in the Reperfused, Isolated Rat Heart
- Decrease in the High Frequency QRS Components Depending on the Local Conduction Delay
- Discordant ST Alternans Contributes to Formation of Reentry -A possible Mechanism of Reperfusion Arrhythmia-
- Electrophysiological effects of sodium channel blockades on anisotropic conduction and conduction block in canine myocardium ; Preferential slowing of longitudinal conduction by flecainide in comparison with disopyramide or lidocaine.
- -1173- THE RELATION BETWEEN THROMBOEMBOLISM AND THERAPEUTIC DRUGS IN PATIENTS WITH TRANSIENT AND/OR CHRONIC ATRIAL FIBRILLATION(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY)
- DIPYRIDAMOLE ELECTROCARDIOGRAPHY TEST FOR THE ASSESSMENT OF THE SEVERITY OF CORONARY ARTERY DISEASE
- 2 Current Status of the Prevalence and Trend of Risk Factors for Cardiovascular Diseases in Nishiarita-Cho Cohort Study(Long-Term Prediction and Prevention of Cardiac Diseases and the Risk Factors,Symposium 10 (SY10) (H),The 70th Anniversary Annual Scient
- Assessment of MEF2A Mutations in Myocardial Infarction in Japanese Patients
- Validation of the Association Between the Gene Encoding 5-Lipoxygenase-Activating Protein and Myocardial Infarction in a Japanese Population
- Epidemiological Evidence of an Association between SLC6A2 Gene Polymorphism and Hypertension
- Dynamic ^I-MIBG SPECT reflects sympathetic nervous integrity and predicts clinical outcome in patients with chronic heart failure
- PE-429 Phosphorylation-independent regulation in cell distribution of signal transducer and activator of transcription (stat) in hypertrophied rabbit heart.(Cardiomyopathy, Basic and Clinical 1 (M) : PE73)(Poster Session (English))
- PE-321 A Pivotal Involvement of Toll-like Receptor-2 in the Pathogenesis of Cuff Induced Vascular Injury(Atherosclerosis, Basic 5 (IHD) : PE55)(Poster Session (English))
- PE-203 AT-1 Receptor Blockade Prevents Cardiac Hypertrophy through Inhibiting Protein Kinase C ε and Extracellular Signal-regulated Kinase in Renal Failure.(Kidney/Renal Circulation 1 (H) : PE35)(Poster Session (English))
- PE-005 Induction of atrial tachyarrythmia was associated with down-regulation of connexin family in dilated left atrium by volume overload(Arrhythmia, Basic 2 (A) : PE1)(Poster Session (English))
- OJ-532 Pitavastatin Inhibits Cardiac Hypertrophy in Rat Model of Progressive Renal Injury through Preventing the Activation of Extracellular-signal Regulated Kinase (ERK)(Kidney/Renal Circulation 3 (H) : OJ65)(Oral Presentation (Japanese))
- Circulating Levels of Soluble Fas Ligand in Cachexic Patients with COPD are higher than those in Non-Cachexic Patients with COPD
- Early Mortality After Acute Myocardial Infarction : Observational Study in Yamagata, 1993-1995
- OE-095 Unique lipoprotein Subclasses Related to Coronary Artery Disease by Component Analysis of Cholesterol Profile in High-performance Liquid Chromatography(Atherosclerosis, clinical-1 (H) OE16,Oral Presentation (English),The 70th Anniversary Annual Sci
- Quantitative detection method of triglycerides in serum lipoproteins and serum-free glycerol by high-performance liquid chromatography
- Effects of the Endothelin Receptor Antagonist Bosentan on Hemodynamics, Symptoms and Functional Capacity in Japanese Patients With Severe Pulmonary Hypertension
- PE-437 Effects of Endothelin Receptor Antagonist Bosentan on Hemodynamics, Symptoms, and Quality of Life in Patients with Severe Pulmonary Hypertension(Pulmonary Circulation 3 (H) : PE74)(Poster Session (English))
- Renal Cholesterol Embolic Disease Effectively Treated with Steroid Pulse Therapy
- Protein Kinase C (PKC) and Extracellular-Signal Regulated Kinase (ERK) Are Involved in Cardiac Hypertrophy of Rat Chronic Renal Failure Model
- 6 Current Status of the Prevalence of Smoking in Nishiarita-Cho Cohort Study and Its Conjunction with Cardiovascular and Cerebrovascular Diseases(Tobacco Free Symposium: The Present Condition of Tobacco Control in Japan, the Risk of Smoking to Cardio-and
- Lesson from the Constitution of Infrastructure of a Large-scale Clinical Trail and a Epidemiological Cohort Study(How to Make Japanese Original Evidence in Cardiology, The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Verification of 525 coding SNPs in 179 hypertension candidate genes in the Japanese population : identification of 159 SNPs in 93 genes
- Association Analysis Between Hypertension and CYBA, CLCNKB, and KCNMB1 Functional Polymorphisms in the Japanese Population : The Suita Study
- Enhanced regional washout of technetium-99m-sestamibi in patients with coronary spastic angina
- Enhanced ^Tc-Sestamibi Washout in Patients with Coronary Spastic Angina
- Myocardial ^Tc-Sestamibi Washout in Patients with Dilated Cardiomyopathy : Comparisons with Endomyocardial Biopsy
- A High Prevalence of Gitelman's Syndrome Mutations in Japanese
- Does C-Reactive Protein Elevation Predict Occurrence of Atrial Structural Remodeling in Patients with Atrial Fibrillation?
- Target LDL-cholesterol Levels in Familial Hypercholesterolemia for Prevention of Cardiovascular Events(Lipid Disorders 2 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- OE-014 Toll-like Receptor-2 Modulates Cytokine Production After Myocardial Infarction(Vasoactive Compound/Growth Factor/Cytokine 1 (H) : OE2)(Oral Presentation (English))
- Fatty Acid Metabolic Imaging and Expression of Fatty Acid Utilization Enzymes in Eccentric Cardiac Hypertrohpy by Volume-Overload
- Differential Regulation of Akt Caused by Two Types of Hemodynamic Overload in Vivo
- Absence of Toll-Like Receptor-2 Modulates Ventricular Remodeling after Myocardial Infarction
- Gender Differences in Cardiovascular Diseases(Gender-specific Meidicine in Cardiovascular Disease, The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- 4 Evaluation of Clinial Indicators using Standardized Prognosis Medhod for Acute Cardiovascular Disease(Clinical Quality Management and Clinical Indicators for Patient Care in Cardiovascular Medicine, The 71st Annual Scientific Meeting of the Japanese Cir
- BODY SURFACE POTENTIAL MAPPING IN PATIENTS WITH ESSENTIAL HYPERTENSION : Electrocardiography (III) : FREE COMMUNICATIONS (IV) : PROCEEDINGS OF THE 49th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Direct Evidence that Sustained Dysfunction of Left Atrial Appendage Contributes to the Occurrence of Cardiogenic Brain Embolism in Patients with Paroxysmal Atrial Fibrillation
- Changes in Lipoprotein Profile after Selective LDL Apheresis
- The KCNB1/E65K Polymorphism is Not Associated With Low Prevalence of Diastolic Blood Pressure in a Japanese Population
- OJ-081 Importance of Pulmonary Veins Region for Atrial Tachyarrythmia Induction and Maintenance in Chronic Volume Overload-Induced Dilated Atria(Arrhythmia, Basic 1 (A) : OJ10)(Oral Presentation (Japanese))
- Hunting for genes for hypertension : the Millennium Genome Project for Hypertension
- Treadmill exercise test using body surface mapping. A quantitative diagnostic method for coronary artery disease.:A Quantitative Diagnostic Method for Coronary Artery Disease
- Comparison of the electrocardiographic changes induced by dipyridamole infusion and treadmill exercise in patients with coronary artery disease.
- Attenuation of exercise-induced R wave increase after diltiazem in effort angina pectoris.
- Determination of the hypertrophic site of the left ventricle by body surface mapping in patients with hypertension.
- Signal-averaged body surface mapping for the assessment of low-amplitude potentials. Relation between ventricular depolarization and repolarization in normal subjects.:Relation between Ventricular Depolarization and Repolarization in Normal Subjects
- Body surface distribution of exercise-induced ST depression in patients with angina pectoris.
- Determination of the left ventricular asynergic site by QRST isointegral mapping in patients with myocardial infarction.
- Angioplasty but Not Thrombolysis Improves Short-term Mortality of Acute Myocardial Infarction. A Multicenter Survey in Yamagata, Japan.
- Relation between the Incidence of Arrhythmias and Ischemic ST-Segment Depression during Dipyridamole Electrocardiography Test in Patients with Coronary Artery Disease.
- Association of ACE Gene Polymorphisms with Coronary Artery Disease in a Northern Area of Japan.
- The Na+-Ca2+ Exchanger Contributes to .BETA.-adrenoceptor Mediated Positive Inotropy in Mouse Heart.