Relation between the Incidence of Arrhythmias and Ischemic ST-Segment Depression during Dipyridamole Electrocardiography Test in Patients with Coronary Artery Disease.
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概要
- 論文の詳細を見る
To examine the incidence of arrhythmias in dipyridamole infusion and the relation between dipyridamole-induced arrhythmias and ST-segment depression, dipyridamole electrocardiography tests were performed on 100 patients with coronary artery disease. Dipyridamole was infused at a rate of 0.568mg/kg for 4min, and 87-lead body surface mapping was performed to determine ischemic ST-segment depression. Positive ischemic response was defined as ≥0.10mV horizontal or downsloping ST-segment depression below the baseline, lasting 80msec after the J point. Arrhythmias were observed by continuous electrocardiographic monitoring using a CM-5 lead electrocardiography. With respect to ventricular premature contractions (VPC), a group of patients with previous myocardial infarction (MI group) had a significantly higher incidence than a group of patients without previous myocardial infarction (non-MI group) before (16.7% vs. 1.7%, p<0.01) and after (38.1% vs. 3.4%, p<0.005) the dipyridamole infusion. The incidence of supraventricular premature contractions (SVPC), however, was not significantly different between the MI and non-MI groups. A group of patients with positive ischemic response had a significantly higher incidence of SVPC after the dipyridamole infusion than a group of patients with negative ischemic response (p<0.005). However, there was no significant difference in the incidence of VPC between the negative and positive ischemic response groups. These results suggest that dipyridamole-induced VPC is not always associated with ischemic ST-segment depression, but dipyridamole-induced SVPC is associated with dipyridamole-induced ischemic ST-segment depression in patients with coronary artery disease.
- International Heart Journal刊行会の論文
著者
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Kubota Isao
First Department of Internal Medicine Yamagata University School of Medicine
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YASUI SHOJI
Nagoya National Hospital
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TSUIKI Kai
First Department of Internal Medicine, Tohoku University School of Medicine
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IKEDA Kozue
First Department of Internal Medicine, Yamagata University School of Medicine
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SHIBATA Takehiko
First Department of Internal Medicine, Yamagata University School of Medicine
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HANASHIMA Kanji
First Department of Internal Medicine, Yamagata University School of Medicine
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YAMAKI Michiyasu
First Department of Internal Medicine, Yamagata University School of Medicine
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