Role of Renin-Angiotensin System in the Controls of Blood Pressure and Aldosterone in Patients with Cirrhosis and Ascites
スポンサーリンク
概要
- 論文の詳細を見る
In an attempt to evaluate the role of renin-angiotensin system in the controls of blood pressure and aldosterone secretion in the patients with cirrhosis and ascctes, 7 patients were infused of an antagonist of angiotensin II, Sar-1 Ile-8 angiotensin II, intravenously to inhibit the action of renin-angiotensin system and to observe changes in arterial pressure and plasma aldosterone. In 1 patient with recent onset of severe ascites and high plasma renin activity, blood pressure and plasma aldosterone decreased during the infusion. In contrast, mild rise in blood pressure and various changes in plasma aldosterone were observed in the other 6 patients with normal plasma renin activity.These results suggest variable angiotensin dependency in the controls of blood pressure and plasma aldosterone in the patients with cirrhosis and ascites according to the stage of the disease, the states of sodium and water balance and/or plasma renin activity.
- International Heart Journal刊行会の論文
著者
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Kato Eiichi
Department Of Internal Medicineicine Keio University School Of Medicine
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Saito Ikuo
Department Of Internal Medicineicine Keio University School Of Medicine
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Saruta Takao
Department Of Clinical Pharmacology Jichi Medical School
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Kondo Kazuoki
Department Of Clinical Pharmacology Jichi Medical Schcol
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Saito Ikuo
Department Of Biotechnology Graduate School Of Engineering Nagoya University
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Kato Eiichi
Dept. Of Intern. Med. School Of Med. Keio Univ.
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Eguchi Toyohisa
Department Of Internal Medicine School Of Medicine Keio University
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Nakamura Ryuichi
Department Of Chemical Engineering Faculty Of Engineering Tokyo Institute Of Technology
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Kato Eiichi
Department Of Internal Medicine School Of Medicine Keio University
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Kato Eiichi
The Department Of Internal Medicine School Of Medicine Keio University
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IYORI Shigeru
Department of Internal Medicine, Keio University School of Medicine
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SAITO Ikuo
Department of Internal Medicine, Keio University School of Medicine
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KONDO Kazuoki
Department of Internal Medicine, Keio University School of Medicine
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NAKAMURA Ryuichi
Department of Internal Medicine, Keio University School of Medicine
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KATO Eiichi
Department of Internal Medicine, Keio University School of Medicine
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加藤 暎一
慶応義塾大学内科
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加藤 暎一
慶応義塾大学医学部内科
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KATO EIICHI
Department of Internal Medicine, School of Medicine, Keio University
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EGUCHI Toyohisa
Department of Internal Medicine, Keio University School of Medicine
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