Association Between Heart Rate and Multiple Risk Factor Syndrome : Cross-Sectional Analysis of a Screened Cohort in Okinawa, Japan

概要

論文の詳細を見る
Background Increased heart rate (HR) and metabolic syndrome are risk factors for cardiovascular morbidity and mortality, but their relationship has not been studied in a large, screened cohort. Methods and Results The association between HR and multiple risk factor syndrome, resembling metabolic syndrome, was examined in participants of a health evaluation program in 1997. Of the 8,432 subjects (5,223 males, 3,209 females, 18-89 years of age), 1,502 (1,185 males, 317 females) were diagnosed with multiple risk factor syndrome and these subjects had higher HR than those without the syndrome (p<0.0001); subjects with a higher number of risk factors had higher HR than those with fewer risk factors (males, p<0.0001; females, p<0.0001). After adjusting for age, sex, and lifestyle factors, subjects within the highest HR quartile had a 2.5-fold higher risk for multiple risk factor syndrome than those in the lowest quartile (p<0.0001). An increase of 10beats/min was associated with an approximately 30% increase in the risk for multiple risk factor syndrome. Conclusions A higher HR is closely associated with multiple risk factor syndrome.
社団法人日本循環器学会の論文
2008-02-20