Relationship Between Serum Cholesterol and the Risk of Acute Myocardial Infarction in a Screened Cohort in Okinawa, Japan
スポンサーリンク
概要
- 論文の詳細を見る
Coronary heart disease(CHD)is rare in Japanese subjects and serum cholesterol levels are low. However, no data have been published relating the effect of serum cholesterol levels to the incidence of acute myocardial infarction(AMI)in Japan. Data from a large community-based mass screening registry are available for the geographically isolated island of Okinawa, Japan(1980 census, 1.11 million). A total of 38, 053 participants(17, 859 men and 20, 194 women)whose serum cholesterol levels were determined in the 1983 mass screening were examined to determine whether they had experienced AMI. Every case of AMI that occurred during a 3-year period(1 April 1988 to March 1991)throughout Okinawa was recorded in a separate registry. The total number of cases of AMI was 1, 021(674 men and 347 women). Of these, 65 patients(41 men and 24 women)were identified by name, sex, birth date, and zip code in the mass screening registry. The cumulative incidence of AMI increased with the serum level of cholesterol:42.1(serum cholesterol ≤167 mg/dl), 133.5(serum cholesterol 168-191 mg/dl), 188.9(serum cholesterol 192-217 mg/dl), and 323.0(serum cholesterol ≥218 mg/dl)per 100, 000 screened subjects. Multiple logistic analysis was conducted to examine the effect of serum cholesterol on the risk of AMI with adjustment for other variables such as sex, age, systolic and diastolic blood pressure, and proteinuria. The adjusted odds ratio(95% confidence interval)of the observed serum levels of cholesterol was 1.66(1.29-2.15)with a reference serum cholesterol level of ≤167 mg/dl. The risk of AMI increased in proportion to the serum level of cholesterol. Serum cholesterol is an independent predictor of AMI in Okinawa, Japan.
- 社団法人日本循環器学会の論文
- 1997-12-20
著者
-
ISEKI Kunitoshi
University of the Ryukyus
-
FUKIYAMA Koshiro
University of the Ryukyus
-
Fukiyama Koshiro
東北大学 薬研究 臨床薬学
-
Fukiyama Koshiro
琉球大学医学部附属病院 血液浄化療法部
-
Fukiyama K
Univ. Ryukyus Okinawa Jpn
-
ISEKI Kunitoshi
Dialysis Unit, University Hospital of The Ryukyus
-
IKEMIYA Yoshiharu
Dialysis Unit and Third Department of Internal Medicine, University Hospital of the Ryukyus
-
IKEMIYA Yoshiharu
Okinawa General Health Maintenance Association
-
Ikemiya Yoshiharu
琉球大学医学部附属病院 第三内科(血液浄化療法部)
-
Ikemiya Y
Dialysis Unit And Third Department Of Internal Medicine University Hospital Of The Ryukyus
-
FUKIYAMA Koshiro
Third Department of Internal Medicine, University of The Ryukyus
-
MURATANI Hiromi
Third Department of Internal Medicine, University of the Ryukyus
-
Okumura Koichiro
Department Of Cardiovascular Medicine Nephrology And Neurology University Of The Ryukyus School Of M
-
IKEMIYA Yosiharu
Okinawa General Health Maintenance Association
-
Iseki Kunitoshi
Dialysis Unit And Third Department Of Internal Medicine University Of The Ryukyus
-
KIMURA Yorio
Third Department of Internal Medicine, University of the Ryukyus School of Medicine
-
Okumura Koichiro
Third Department of Internal Medicine, University of the Ryukyus School of Mechcine
-
Wakugami Kiyoshi
Third Department of Internal Medicine, University of the Ryukyus School of Mechcine
-
Fukiyama Kohshiro
Japan Seaman's Relief Association Moji Hospital
-
Fukiyama Koshiro
Third Department Of Internal Medicine University Of The Ryukyus School Of Medicine
-
OKUMURA Koichiro
琉球大学医学部 第三内科
-
Muratani Hiromi
Third Department Of Internal Medicine University Of The Ryukyus School Of Medicine
-
Kimura Yorio
Third Department Of Internal Medicine University Of The Ryukyus School Of Medicine
-
Wakugami Kiyoshi
Department Of Cardiovascular Medicine Nephrology And Neurology University Of The Ryukyus School Of M
-
ISEKI Kunitoshi
Dialysis Unit
関連論文
- The Japanese Society of Hypertension Committee for Guidelines for the Management of Hypertension
- Effects of candesartan and amlodipine on cardiovascular events in hypertensive patients with chronic kidney disease : subanalysis of the CASE-J Study
- Clinical Practice Guidebook for Diagnosis and Treatment of Chronic Kidney Disease
- Chronic kidney disease perspectives in Japan and the importance of urinalysis screening
- Prevalence of chronic kidney disease (CKD) in the Japanese general population predicted by the MDRD equation modified by a Japanese coefficient
- Geographic difference in the prevalence of chronic kidney disease among Japanese screened subjects : Ibaraki versus Okinawa
- Estimation of glomerular filtration rate by the MDRD study equation modified for Japanese patients with chronic kidney disease
- Effect of heart rate on the risk of developing metabolic syndrome
- Decreased body mass index as an independent risk factor for developing chronic kidney disease
- PJ-131 Cardiometabolic Effects Induced by Lower and Extremely Lower Doses of Diuretics in Uncontrolled Hypertension Treated with Angiotensin II Receptor Blockers(Hypertension, clinical(07)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of
- Association Between Heart Rate and Multiple Risk Factor Syndrome : Cross-Sectional Analysis of a Screened Cohort in Okinawa, Japan
- Higher Heart Rate Predicts the Risk of Developing Hypertension in a Normotensive Screened Cohort
- Metabolic Syndrome and Risk of Developing Chronic Kidney Disease in Japanese Adults
- Response to : The Contribution of Nutrition to the Protective Value of High Plasma Aldosterone Concentrations in Hemodialysis Patients
- Risk of Developing Low Glomerular Filtration Rate or Elevated Serum Creatinine in a Screened Cohort in Okinawa, Japan
- Changes in the Demographics and Prevalence of Chronic Kidney Disease in Okinawa, Japan (1993 to 2003)
- Proteinuria as a Significant Determinant of Hypertension in a Normotensive Screened Cohort in Okinawa, Japan
- Angiotensin I-Converting Enzyme Inhibitor Improves Reactive Hyperemia in Elderly Hypertensives with Arteriosclerosis Obliterans
- Plasma Aldosterone in Hypertensive Patients on Chronic Hemodialysis : Distribution, Determinants and Impact on Survival
- PJ-701 Seasonal and Circadian Variations of the Onset of Acute Myocardial Infarction in Okinawa(Preventive medicine/Epidemiology/Education-6 (H) PJ118,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Soc
- OE-331 Dynamic Binding of Nuclear Matrix Proteins to Chromatin DMA Induced by cyclic Stretch in Rat Cardiovascular Cells(Molecular biology, myocardium-1 (M) OE56,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Ci
- Silent information regulator, Sirtuin1, and age-related diseases
- Immobilization Stress Inhibits Intimal Fibromuscular Proliferation in the Process of Arterial Remodeling in Rats
- Serum Cholesterol and Risk of End - Stage Renal Disease in a Cohort of Mass Screening
- Impact of Multiple Risk Factor Clustering on the Elevation of Blood Pressure
- End-stage Renal Disease Associated with Familial Mediterranean Fever
- Family History of Hypertension and Blood Pressure in a Screened Cohort
- Relationship between dyslipidemia and the risk of developing end-stage renal disease in a screened cohort
- Severe Abdominal Pain Associated with Allergic Reaction to Nafamostat Mesilate in a Chronic Hemodialysis Patient
- Prevalence and Correlates of Diabetes Mellitus in a Screened Cohort in Okinawa, Japan
- Significance of Hyperuricemia on the Early Detection of Renal Failure in a Cohort of Screened Subjects
- High Heart Rate Relates to Clustering of Cardiovascular Risk Factors in a Screened Cohort
- Improved long-term survival rate of chronic dialysis patients with diabetes mellitus
- Long-term survival of chronic dialysis patients in comparison to that of stroke and acute myocardial infarction patients
- Non-Corresponding Effects of an Angiotensin-Converting Enzyme Inhibitor on Cardiac and Vascular Hypertrophy in Spontaneously Hypertensive Rats
- Prevalence of hospitalization and prognosis of patients on chronic dialysis
- An epidemiologic analysis of parathyroidectomy in chronic dialysis patients
- Hyperuricemia as a Predictor of Hypertension in a Screened Cohort in Okinawa, Japan
- Hyperuricemia and Triglyceride to High-density Lipoprotein Ratio in Subjects with Metabolic Syndrome in Screened Cohort in Okinawa, Japan(Metabolism/Biochemistry/Energetics 1 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Hyperuricemia and Cardiovascular Risk Factor Clustering in a Screened Cohort in Okinawa, Japan
- PJ-448 Hyperuricemia as a predictor of developing hypertension in a screened cohort in Okinawa, Japan(Preventive Medicine/Epidemiology/Education 4 (H) : PJ75)(Poster Session (Japanese))
- PE-148 Electrocardiographic Left Ventricular Hypertrophy as a Risk Factor of the Development of Proteinuria among Normotensive Screened Subjects(Preventive Medicine/Epidemiology/Education 1 (H) : PE26)(Poster Session (English))
- OJ-409 Higher Heart Rate Is Associated with the Development of Hypertension in Normotensive Screened Subjects(Preventive Medicine/Epidemiology/Education 3 (H) : OJ50)(Oral Presentation (Japanese))
- High Pulse Pressure Is a Predictor of Subsequent Development of Hypertension in Normotensive Screened Subjects
- Cardiovascular Risk Factors Associated with Pulse Pressure in a Screened Cohort in Okinawa, Japan
- 3 Clinical Outcomes in Hypertensive Patients with High Cardiovascular Risks : Principal Results of Candesartan Antihyopertensive Survival Evaluation in Japan (CASE-J) Study(Late Breaking Clinical Trials in Japan, The 71st Annual Scientific Meeting of the
- The Optimal Target Blood Pressure for Antihypertensive Treatment in Japanese Elderly Patients with High-Risk Hypertension : A Subanalysis of the Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) Trial
- Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) Trial of Cardiovascular Events in High-Risk Hypertensive Patients : Rationale, Design, and Methods
- Slower Decline of Glomerular Filtration Rate in the Japanese General Population : A Longitudinal 10-Year Follow-Up Study
- Estimated Protein Intake and Blood Pressure in a Screened Cohort in Okinawa, Japan
- Urinary Excretion of Sodium and Potassium in a Screened Cohort in Okinawa, Japan
- The Renin-Angiotensin-Aldosterone System and Circadian Rhythm of Urine Variables in Normotensive and Hypertensive Subjects : SYMPOSIUM ON BLOOD PRESSURE AND VASOACTIVE SUBSTANCES
- Salt Intake and Hypertension : Pathophysiology of Hypertension and its Relation to the Choice of Antihypertensive Treatment
- Risk Factors for Stiffness of the Wall of the Thoracic Aorta in Patients With Mild Atherosis
- Factors Related to Impairment of Activities of Daily Living
- Divergent Effects of Beta-Blocker Therapy on Self-Estimated and Objectively Scored Activities of Daily Living
- P692 FACTORS CONTRIBUTING TO THE PROGRESSION RATE OF CORONARY ARTERY STENOSIS
- 0322 SMOKING IMPAIRS ADL (ACTIVITIES OF DAILY LIVING)
- Current Status of Antihypertensive Therapy for Elderly Patients in Japan
- Increase in Pulse Pressure Relates to Diabetes Mellitus and Low HDL Cholesterol, but Not to Hyperlipidemia in Hypertensive Patients Aged 50 Years or Older
- Office Blood Pressure Variability as a Predictor of Brain Infarction in Elderly Hypertensive Patients
- Control of Blood Pressure and Lifestyle-Related Risk Factors in Elderly Japanese Hypertensive Subjects
- Comparison of the Effect of Blood Pressure on the Development of Stroke, Acute Myocardial Infarction, and End-Stage Renal Disease
- Low Serum Cholesterol as a Risk Factor for Hemorrhagic Stroke in Men : A Community-Based Mass Screening in Okinawa, Japan
- Outcome of Subjects with Elevated Serum Creatinine in a Community-Based Mass Screening
- Relationship Between Serum Cholesterol and the Risk of Acute Myocardial Infarction in a Screened Cohort in Okinawa, Japan
- Experimental Studies on the Responses of Blood Pressure Elevation Following an Occlusion of the Arteries at the Base of the Brain : Part III
- 127. Studies on Brain Circulation (VI) : (1) Basilar Blood Flow in Renoprival Dogs : (2) Studies on Brain Circulation in Patients with Cerebral Vascular Accidents by External Counting Method Using RISA
- Olmesartan clinical trial in Okinawan patients under OKIDS (OCTOPUS) study : design and methods
- A community-based evaluation of the effect of renal transplantation on survival in patients with renalreplacement therapy
- Japanese Society of Hypertension (JSH) Guidelines for Self-Monitoring of Blood Pressure at Home
- Tolerability and Safety of a Calcium Channel Blocker in Comparison with a Diuretic in the Treatment of Elderly Ptients with Hypertension : Secondary Analysis of the NICS-EH
- Arrhythmogenic Right Ventricular Dysplasia Presenting as Regression of Left Ventricular Dysfunction: A Case Report
- Cardiovascular and Sympathetic Effects of _L-Glutamate and Glycine Injected into the Rostral Ventrolateral Medulla of Conscious Rats
- Ouabain-Like Immunoreactivity in the Medulla Oblongata of Rats
- SUPPRESSED SYMPATHETIC FUNCTION IN WISTAR RATS BRED SUCCESSIVELY ON LOW SALT DIET : Hypertension (II) : FREE COMMUNICATIONS (II) : PROCEEDINGS OF THE 49th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Augmented Sympathetic Nervous Function in Young Subjects with Borderline Hypertension : THE 11th CONFERENCE ON THE PATHOGENESIS OF HYPERTENSION
- Guidelines for Hypertension in the Elderly : 1999 Revised Version
- evidence-based practice guideline for the treatment of chronic kidney disease
- EVALUATION OF PLASMA RENIN ACTIVITY BY BLOOD PRESSURE LEVEL (PRESSURE-RENIN INDEX) IN PATIENTS WITH ESSENTIAL HYPERTENSION
- RENIN RESPONSE TO FUROSEMIDE DIFFERS WITH THE ROUTES OF ADMINISTRATION IN HEALTHY MEN
- -240-DIFFERENCE OF RENIN SECRETION DURING SYSTEMIC INFUSION OF ANGIOTENSIN II ANALOGUE IN ESSENTIAL HYPERTENSION : Renin,Angiotensin : PROCEEDINGS OF THE 42nd ANNUAL MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Plasma Dopamine-β-Hydroxylase Activity in Normal Young Men : Its Responsiveness to Manipulation of Sodium Balance and Upright Posture
- Hypotensive Response to Angiotensin II Analogue in Benign Essential Hypertension
- EFFECTS OF TREATMENT IN MALIGNANT HYPERTENSION CAUSED BY DIFFERENT ETILOGIES : IIIrd Auditorium : PROCEEDINGS OF THE 40TH ANNUAL MEETING OF THE JAPANESE CIRCULATION SOCIETY
- ANTIHYPERTENSIVE ACTION OF ANGIOTENSIN II INHIBITOR IN HYPERTENSIVE PATIENTS
- Experimental Study on Neural Control of Renin Release
- Design and methods of a strategic outcome study for chronic kidney disease : Frontier of Renal Outcome Modifications in Japan
- Prevalence of anemia according to stage of chronic kidney disease in a large screening cohort of Japanese
- Prevalence of chronic kidney disease in the Japanese general population
- Heart rate as a risk factor for developing chronic kidney disease : longitudinal analysis of a screened cohort
- Mental Stress Inhibits the Intimal Fibromuscular Proliferation through Endogenous Opioid System in the Process of Arterial Remodeling
- Impact of high coronary artery calcification score (CACS) on survival in patients on chronic hemodialysis
- Hypertension in dialysis patients:a cross-sectional analysis
- Coronary artery calcium scoring is useful for predicting coronary artery disease in hemodialysis patients with chest pain
- Significance of past history of renal failure for the detection of high-risk individuals for cardiovascular and end-stage renal disease : analysis of data from a nationwide health checkup
- Cost-effectiveness of chronic kidney disease mass screening test in Japan
- Weight gain after 20 years of age is associated with prevalence of chronic kidney disease
- Risk factor profiles based on estimated glomerular filtration rate and dipstick proteinuria among participants of the Specific Health Check and Guidance System in Japan 2008
- Association of severe hypertension with pneumonia in elderly patients with acute ischemic stroke