Practical Risk Prediction Tools for Coronary Heart Disease in Mild to Moderate Hypercholesterolemia in Japan : Originated From the MEGA Study Data
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概要
- 論文の詳細を見る
Background A simple and practical risk prediction tool for coronary heart disease (CHD) to determine the specific risk level in each patient that fits the true clinical practice setting is needed and would be valuable in Japan. Methods and Results A 5-year risk prediction score and chart for CHD based on the MEGA study data was developed in the present study. The MEGA risk prediction score and chart were constructed based on the coefficient of each risk factor. The risk factors included in these risk prediction tools were: treatment (diet, diet plus pravastatin), sex, age, baseline high-density lipoprotein-cholesterol, baseline low-density lipoprotein-cholesterol, glucose abnormality (diabetes and impaired fasting glucose), hypertension, and smoking. The MEGA risk prediction score comprised the risk score for each risk factor, and it can predict 5-year risk for CHD with 5 levels of risk, based on the total risk score. The MEGA risk prediction chart more accurately predicts risk, by reflecting the accumulation of risk factors and using an 8-color visual chart. Conclusions The MEGA risk prediction score and chart, developed from the MEGA study data, more easily and accurately assesses the 5-year CHD risk in mild to moderate hypercholesterolemic patients in the usual clinical practice setting in Japan.
- 社団法人日本循環器学会の論文
- 2008-09-20
著者
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Nakaya Noriaki
Nakaya Clinic
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MIZUNO Kyoichi
Department of Internal Medicine, Nippon Medical School
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OHYA Yusuke
University of the Ryukyus
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TERAMOTO Tamio
Department of Internal Medicine, Teikyo University
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Ohashi Yasuo
Department of Biostatistics/Epidemiology and Preventive Health Sciences, School of Health Sciences a
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Ohya Yusuke
Department Of Cardiovascular Medicine Nephrology And Neurology School Of Medicine University Of The
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Nakaya Noriaki
Department Of Internal Medicine Tokai University School Of Medicine
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OKUBO Yasuhiro
Utsunomiya Committee on Renal Disease Prevention
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Ouchi Yasuyoshi
東京大学 医学部泌尿器科学
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Ouchi Y
Department Of Geriatric Medicine Graduate School Of Medicine University Of Tokyo
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NAKAMURA HARUO
Keio Univ.
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Nakamura Haruo
Mitsukoshi Health And Welfare Foundation
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Teramoto T
Dep. Of Internal Medicine Teikyo Univ. School Of Medicine
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Teramoto Tamio
帝京大学 医学部内科
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Teramoto Tamio
Department Of Internal Medicine Teikyo University School Of Medicine
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TERAMOTO Tamio
Committee for Epidemiology and Clinical Management of Atherosclerosis
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Mizuno Kyoichi
Department Of Medicine Nippon Medical School
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Nakamura Haruo
Department Of Medicine Aoto Hospital Jikei University Tokyo Japan
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Yokoyama Shinji
Biochemistry, Cell Biology and Metabolism, Nagoya City University Graduate School of Medical Science
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Okubo Yasuhiro
Department Of Geriatric Medicine University Of Tokyo
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Ohashi Yasuo
Department Of Biostatistics Epidemiology And Preventive Health Sciences The University Of Tokyo
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Nakayam Noriaki
Nakaya Clinic
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Mizuno Kyoichi
Department Of 1st Internal Medicine Nippon Medical School
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Teramoto Tamio
First Department Of Internal Medicine Teikyo University School Of Medicine
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Nayaka Noriaki
Nakaya Clinic
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Okubo Yasuhiro
Department Of Geriatric Medicine The University Of Tokyo
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Yokoyama Shinji
Biochemistry 1 Nagoya City University Graduate School Of Medical Sciences
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Ohashi Yasuo
Department Of Biostatistics Epidemiology And Preventive Health Sciences And Nursing University Of To
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Ohashi Yasuo
Department Of Biostatistics / Epidemiology And Preventive Health Sciences School Of Health Sciences
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Okubo Yasuhiro
University Of Tokyo
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Nakamura Haruo
First Department Of Internal Medicine National Defence Medical College
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