The Pathogenesis of an Impending Infarction and its Treatment : An angioscopic analysis : PATHOGENESIS AND MANAGEMENT OF IMPENDING MYOCARDIAL INFARCTION

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概要

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• To clarify the pathogenesis of an impending infarction and to investigate the difference between the pathogenesis of an acute myocardial infarction and an impending infarction, we have performed percutaneous transluminal coronary angioscopy in 13 patients with an impending infarction and in 13 patients with an acute myocardial infarction. As a result, coronary thrombi were observed in 12 of the 13 patients with an impending infarction, and a similar frequency of thrombi was observed in the patients with an acute myocardial infarction. Further, grayish white thrombi were observed in 9 of 12 patients with an impending infarction, but no such thrombi were noted in those with an acute myocardial infarction. Reddish thrombi, however, were observed in all patients with acute myocardial infarction, whereas such thrombi were observed in only 3 of 12 patients with an impending infarction. Informatively, occlusive thrombi occurred more frequently in patients with an acute myocardial infarction than in those with an impending infarction. As a thrombus plays an important role in an impending infarction, we also evaluated the effect of anticoagulant and thrombolytic therapy for an impending infarction in 79 patients. The incidence of recurrent angina and a subsequent acute myocardial infarction were significantly higher in non-heparin-treated patients and in thrombolytic-treated patients than in heparin-treated patients. In conclusion, a thrombus plays an important role in the pathogenesis of an impending infarction and in an acute myocardial infarction, though the characteristics of the thrombus differ in each instance. This difference may account for the differing results of thrombolytic therapy. Heparin was found an effective treatment for myocardial ischemia in an impending infarction.

• 社団法人日本循環器学会の論文
• 1992-11-20

著者

• Hikita Hiroyuki

  Department of Cardiology, Yokosuka Kyosai Hospital

• MIZUNO Kyoichi

  Department of Internal Medicine, Nippon Medical School

• Mizuno Kyoichi

  Department Of Medical Engineering National Defense Medical College Graduate School

• Mizun Kyoichi

  Department Of Medical Engineering National Defense Medical College Graduate School

• Nakamura Haruo

  Department of Cardiovascular Surgery, Toranomon Hospital

• Kurita Akira

  National Defense Medical College Research Institute, Division of Biomedical Engineering

• Nakamura Haruo

  Mitsukoshi Health And Welfare Foundation

• Satomura Kimio

  Department of Cardiovascular Medicine, National Defense Medical College

• Arakawa Koh

  Department of Cardiovascular Medicine, National Defense Medical College

• KURITA AKIRA

  Department of Internal Medicine, National Defense Medical College

• Shibuya Toshio

  First Department Of Internal Medicine National Defence Medical College

• MIYAMOTO Akira

  Department of Applied Chemistry, Graduate School of Engineering, Tohoku University

• Satomura Kimio

  National Defense Medical College Research Institute Division Of Biomedical Engineering And Internal

• Satomura Kimio

  Internal Medicine I National Defense Medical College

• Miyamoto Akira

  The First Department Of Internal Medicine Department Of Medical Engineering

• Mizun Kyoichi

  Cedars-sinai Medical Center And National Defense Medical College

• Kurita Akira

  Department Of Internal Medicine Nippon Medical School

• Arakawa Koh

  Department Of Medicine 1 Division Of Cardiology National Defense Medical College

• Arakawa Koh

  Department Of Cardiology National Defense Medical College

• Hikita Hiroyuki

  The First Department Of Internal Medicine National Defense Medical College

• SHIBUYA TOSHIO

  Department of Emergency Medicine, The First Department of Internal Medicine, National Defense Medica

• Mizuno Kyoichi

  Department Of 1st Internal Medicine Nippon Medical School

• Arakawa Kou

  The 1st Dept. of Intern. Med.

• Miyamoto Akira

  Department Of Applied Chemistry Graduate School Of Engineering Tohoku University

• Shibuya Toshio

  Medicine I National Defense Medical College

• Nakamura Haruo

  Department Of Internal Medicine-i National Defense Medical College

• Nakamura Haruo

  The Department Of Internal Medicine I National Defense Medical College

• Nakamura Haruo

  Department Of Cardiovascular Surgery Toranomon Hospital

• Nakamura Haruo

  First Department Of Internal Medicine National Defence Medical Collage

• Satomura Kimio

  First Department Of Internal Medicine And The First Department Of Anatomy National Defense Medical C

• Arakawa Ko

  Department Of Medicine 1 National Defense Medical College

• Shibuya Toshio

  The 1st Dept. Of Intern. Med.

• Kikuchi Makoto

  Department Of Medical Engineering National Defense Medical College Graduate School

• Mizuno Kyoichi

  Department Of Emergency

• Kikuchi Makoto

  Department Of Medical Engineering National Defense Medical College

• Arakawa Koh

  First Department Of Internal Medicine National Defense Medical College

• Satomura Kirnio

  First Department Of Internal Medicine And The First Department Of Anatomy National Defense Medical C

• Kurita Akira

  Department Of Information Science Fukui University

• Kurita Akira

  Department Of Cardiology Nippon Medical School

• Satomura Kimio

  First Department Of Internal Medicine And The First Department Of Anatomy National Defense Medical C

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