High-Frequency Genetic Contents Variations in Clinical Candida albicans Isolates
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概要
- 論文の詳細を見る
Genome plasticity is a hallmark of Candida albicans and is believed to be an adaptation strategy. But the extent of such genomic variability is not well investigated. In this study, genetic contents of clinical C. albicans isolates were investigated at whole-genome level with array-based comparative genomic hybridization (array CGH) technology. It was revealed that C. albicans possessed variations of genetic contents, as well as aneuploidy. The variable genes were scattered across the chromosomes, as well clustered in particular regions, including sub-telomeric regions, retrotransposon-insertion sites and a variable region on chromosome 6.
- 公益社団法人 日本薬学会の論文
著者
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YANG Feng
Department of Materials Physics and Chemistry, University of Science and Technology Beijing
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Wang Yan
Department Of Electrical Engineering National Cheng Kung University
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YAN Lan
Department of Pharmacology, College of Pharmacy, Second Military Medical University
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Yang Feng
Department Of Electronic Engineering Tsinghua National Laboratory For Information Science And Techno
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Wang Yan
Department Of Cardiovascular Sciences Oita University School Of Medicine
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Yan Lan
Department Of Pharmacology College Of Pharmacy Second Military Medical University
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Yan Tian-Hua
Department of Pharmacology, School of Pharmacy, China Pharmaceutical University
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Rustchenko Elena
Department of Biochemistry and Biophysics, School of Medicine and Dentistry, University of Rochester
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Gao Ping-Hui
Department of Pharmacology, School of Pharmacy, Second Military Medical University
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Cao Ying-Ying
Department of Pharmacology, School of Pharmacy, Second Military Medical University
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Wang Qiu-Juan
Department of Pharmacology, School of Pharmacy, Second Military Medical University
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Ji Hui
Department of Pharmacology, School of Pharmacy, China Pharmaceutical University
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Cao Yong-Bing
Department of Pharmacology, School of Pharmacy, Second Military Medical University
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Jiang Yuan-Ying
Department of Pharmacology, School of Pharmacy, Second Military Medical University
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Ji Hui
Department Of Pharmacology China Pharmaceutical University
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Wang Yan
Department Of Biology Graduate University Of Chinese Academy Of Sciences
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Wang Yan
Department of Pharmacology, School of Pharmacy, Second Military Medical University
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Yan Lan
Department of Pharmacology, School of Pharmacy, Second Military Medical University
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Rustchenko Elena
Department of Biochemistry and Biophysics, School of Medicine and Dentistry, University of Rochester Medical School
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Yang Feng
Department of Pharmacology, School of Pharmacy, China Pharmaceutical University
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