Induction of Primer Pheromone Production by Dihydrotestosterone in the Male Goat.
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概要
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Castrated goats were treated with dihydrotestosterone (DHT) for four weeks. Skin samples were collected from the head and the rump regions before and after the DHT treatment. The primer pheromone activities of these samples were assessed neurophysiologically by recording electrophysiological manifestations of the hypothalamic gonadotropin-releasing hormone (GnRH) pulse generator activity. Pheromone activity was detected in both the head and rump skin samples following the DHT treatment, although the development of sebaceous glands was limited to the head region. Taken together with our previous finding that testosterone treatment results in the appearance of primer pheromone activity in the skin sample of the head region but not of the rump region, these observations suggests that the regional difference of pheromone production would be ascribed to intrinsic expression levels of 5α-reductase, an enzyme converting testosterone to DHT.
- 公益社団法人 日本獣医学会の論文
著者
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IWATA Eri
Laboratory of Veterinary Ethology, The University of Tokyo
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Iwata Eri
Laboratory Of Marine Microbiology Division Of Applied Biosciences Graduate School Of Agriculture Kyo
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Takeuchi Yukari
Laboratory Of Veterinary Ethology The University Of Tokyo
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Wakabayashi Yoshihiro
Laboratory Of Neurobiology National Institute Of Agrobiological Sciences
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Mori Yuji
Laboratory of Physical Chemistry Tokyo Institute of Technology
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MATSUSE Souichiro
Laboratory of Veterinary Ethology, The University of Tokyo
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KIKUSUI Takehumi
Laboratory of Veterinary Ethology, The University of Tokyo
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