Immunohistochemical Localization and Gene Expression of Carbonic Anhydrase Isoenzymes CA-II and CA-VI in Canine Lower Airways and Lung

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概要

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• The immunohistolocalization and gene expression of carbonic anhydrase (CA) isoenzymes CA-II and CA-VI in the canine lower airways and lung were examined using specific canine CA-II and CA-VI antisera and the RT-PCR method. Laryngeal, tracheal and bronchial epithelia, serous acinar and bronchiolar secretory cells and pulmonary great alveolar cells showed immunopositive reactions to anti-CA-II and anti-CA-VI antisera. However, all mucous cells showed immunonegative reactions. The physiological roles of CA-II and CA-VI in the lower airways and lung may involve the maintenance of pH balance and the protection of mucosal surfaces against the acidic milieu.

• 社団法人　日本獣医学会の論文

著者

• Soeta Satoshi

  Department Of Veterinary Anatomy Nippon Vetrinary And Animal Science University

• Amasaki Hajime

  Department Of Veterinary Anatomy Nippon Veterinary & Animal Science University

• Ichihara Nobutsune

  Department Of Anatomy I School Of Veterinary Medicine Azabu University

• Oishi Motoharu

  Department Of Veterinary Anatomy 1st School Of Veterinary Medicine Azabu University

• NISHITA Toshiho

  Department of Physiology 1, School of Veterinary Medicine, Azabu University

• ASARI Masao

  Department of Anatomy 1, School of Veterinary Medicine, Azabu University

• Oishi Motoharu

  Department Of Anatomy 1st School Of Veterinary Medicine Azabu University

• Murakami Masaru

  Department Of Cardiology Tokushima Prefectural Central Hospital

• SUGIURA Yosuke

  Department of Anatomy, School of Veterinary Medicine, Azabu University

• AMASAKI Tomoko

  Department of Clinical Engineering, Tokyo Electronics College

• MURAKAMI Masaru

  Department of Molecular Biology, School of Veterinary Medicine, Azabu University

• SOETA Satoshi

  Department of Veterinary Anatomy, Nippon Veterinary and Life Science University

• ICHIHARA Nobutsune

  Department of Anatomy, School of Veterinary Medicine, Azabu University

• ICHIHARA Nobutsune

  Department of Anatomy 1, School of Veterinary Medicine, Azabu University

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