Diketopiperazine Alkaloids from a Deep Ocean Sediment Derived Fungus Penicillium sp.
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概要
- 論文の詳細を見る
Five new diketopiperazine alkaloids, brevicompanines D—H (3—7), together with two known analogs, allo-brevicompanine B (1) and fructigenine B (2), were isolated from a deep ocean sediment derived fungus Penicillium sp. Their structures were established by spectroscopic methods including 2D NMR and chiral HPLC analysis. Compounds 4 and 7 inhibited lipopolysaccharide (LPS)-induced nitric oxide production in BV2 microglial cells.
- 公益社団法人 日本薬学会の論文
著者
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Xiao Xiang
Key Lab. Of Marine Biogenetic Resources The Third Inst. Of Oceanography The State Oceanic Administra
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Du Lin
Key Laboratory Of Marine Drugs Chinese Ministry Of Education School Of Medicine And Pharmacy Ocean U
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Park Hyun
Department Of Computer Science Korea Advanced Institute Of Science & Technology
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Gu Qianqun
Key Laboratory Of Marine Drugs Chinese Ministry Of Education ; Institute Of Marine Drugs And Food Oc
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Wang Fengping
Key Lab. Of Marine Biogenetic Resources The Third Inst. Of Oceanography The State Oceanic Administra
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Zhu Tianjiao
Key Laboratory Of Marine Drugs Chinese Ministry Of Education ; School Of Medicine And Pharmacy Ocean
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Yang Xinying
Department of Infection Biology, Zoonosis Research Center, Wonkwang University School of Medicine
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Park Hyun
Department Of Computer Science Chungnam National University
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Park Hyun
Department Of Chemical & Biomolecular Engineering Korea Advanced Institute Of Science & Tech
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Park Hyun
Department Of Ceramic Engineering Chonnam National University
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Park Hyun
Department of Biotechnology, Yeungnam University
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Gu Qianqun
Key Laboratory of Marine Drugs, Chinese Ministry of Education, Institute of Marine Drugs and Food, Ocean University of China
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Xiao Xiang
Key Laboratory of Marine Biogenetic Resources, the Third Institute of Oceanography, the State Oceanic Administration
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Wang Fengping
Key Laboratory of Marine Biogenetic Resources, the Third Institute of Oceanography, the State Oceanic Administration
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Zhu Tianjiao
Key Laboratory of Marine Drugs, Chinese Ministry of Education, Institute of Marine Drugs and Food, Ocean University of China
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