Antioxidative Constituents from the Aerial Part of Piper elongatum VAHL.
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概要
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Six aromatic compounds, asebogenin (1), 2',6'-dihydroxy-4'-methoxydihydrochalcone (2), 3-geranyl-4-methoxy-benzoic acid (3), 3-geranyl-4-hydroxybenzoic acid (4), nervogenic acid (5) and 2,2-dimethyl-6-carboxyl-8-prenyl-chromene (6) were isolated from the methanol extract of the aerial part of <I>Piper elongatum</I> VAHL., whose leaves are used as a folk medicine in South America. The structures of 1-6 were elucidated by MS, <SUP>1</SUP>H-NMR and <SUP>13</SUP>C-NMR spectroscopies, and chemical evidence. Among these compounds, 1 showed stronger antioxidative activity than that of α-tocopherol, and 4 and 5 exhibited higher activity than that of <I>t</I>-butyl-4-hydroxyanisole (BHA) using the ferric thiocyanate method.
著者
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Masuoka Chikako
School Of Agriculture Tokai University
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Nohara Toshihiro
Faculty of Medical and Pharmaceutical Scieces, Sojo University
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Ito Yasuyuki
Research Institute of General Education Kyushu Tokai University
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ONO Masateru
Research Institute of General Education
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