Antioxidative, Antihyaluronidase and Antityrosinase Activities of Some Constituents from the Aerial Part of Piper elongatum VAHL.
スポンサーリンク
概要
- 論文の詳細を見る
Seven known compounds, pyrroside B (1), swertisin (2), isovitexin (3), isoswertiajaponin (4), vomifoliol (blumenol A) (5), (6S,9R)-roseoside (6) and angelicoidenol (7) were isolated from the methanol (MeOH) extract of the aerial part of Piper elongatum VAHL. and their structures were identified on the basis of physical and spectral data. In addition, the antioxidative activity of 1–4 was evaluated by the ferric thiocyanate method. All these compounds showed stronger antioxidative activity than that of α-tocopherol. Furthermore, the scavenging effects on 1,1-diphenyl-2-picrylhydrazyl (DPPH), the antihyaluronidase and the antityrosinase activities of 1–4, asebogenin (8), 2′,6′-dihydroxy-4′-methoxydihydrochalcone (9), 3-geranyl-4-methoxybenzoic acid (10), 3-geranyl-4-hydroxybenzoic acid (11), nervogenic acid (12) and 2,2-dimethyl-6-carboxyl-8-prenyl-chromene (13), which were previously isolated from the MeOH extract were evaluated. Compounds 4, 8 and 9 showed higher radical scavenging effect than that of L-cysteine, and 4, 8 and 11 exhibited stronger inhibition effect on the activation of hyaluronidase than that of tranilast. Compound 8 indicated almost the same antityrosinase activity as that of kojic acid.
- 社団法人 日本食品科学工学会の論文
- 2003-05-01
著者
-
Nohara Toshihiro
Faculty of Pharmaceutical Sciences, Sojo University
-
MASUOKA Chikako
School of Agriculture, Tokai University
-
ONO Masateru
School of Agriculture, Tokai University
-
Nagamatsu T
Department Of Pharmacobiology And Therapeutics Faculty Of Pharmacy Meijo University
-
Nagao Toshiyuki
Department Of Pharmacology Faculty Of Pharmacy Meijo University
-
Nagamatsu T
Department Of Pharmacology Faculty Of Pharmacy Meijo University
-
Masuoka C
School Of Agriculture Tokai University
-
Masuoka Chikako
東海大学 農学部
-
Masuoka Chikako
School Of Agriculture Tokai University
-
ITO Yasuyuki
School of Agriculture, Kyushu Tokai University
-
Ito Yasuyuki
School Of Agriculture Kyushu Tokai University
-
Nohara Toshihiro
Faculty Of Medical And Pharmaceutical Science Kumamoto University
-
Ono Masateru
School Of Agriculture Kyushu Tokai University
-
Nohara Toshihiro
Faculty of Medical and Pharmaceutical Scieces, Sojo University
関連論文
- Four New ent-Kaurane Diterpenoids from the Fruits of Annona cherimola
- Microbial transformation and bioactivation of isoflavones from Pueraria flowers by human intestinal bacterial strains
- Dolabellane Diterpene and Three Cycloartane Glycosides from Thalictrum squarrosum
- Cyclodextrin-Enclosed Substances of Brazilian Propolis
- Two Novel Long-Chain Alkanoic Acid Esters of Lupeol from Alecrim-Propolis
- Pharmacological Study on the Novel Antinociceptive Agent, a Novel Monoterpene Alkaloid from Incarvillea sinensis(Pharmacognosy)
- A new diterpenoid and a new triterpenoid glucosyl ester from the leaves of Callicarpa japonica Thunb. var. luxurians Rehd.
- A new lignan glucoside from the stems of Callicarpa japonica Thunb. var. luxurians Rehd.
- Five New Diterpenoids, Viteagnusins A-E, from the Fruit of Vitex agnus-castus
- HPLC Profile Analysis of Hepatoprotective Oleanene-Glucuronides in Puerariae Flos
- Two New 15, 16-Seco-cycloartane Glycosides from Cimicifuga Rhizome
- Four New Cycloartane Glycosides from Aquilegia vulgaris and Their Immunosuppressive Activities in Mouse Allogeneic Mixed Lymphocyte Reaction
- Three Cycloartane Glycosides from Cimicifuga Rhizome and Their Immunosuppressive Activities in Mouse Allogeneic Mixed Lymphocyte Reaction
- Three New Anti-Oxidative Saponarin Analogs from Young green Barley Leaves
- Structures of Three New Oleanene Glucuronides Isolated from Lathyrus palustris var. pilosus and Hepatoprotective Activity
- A New Oleanene Glucuronide Having a Branched-Chain Sugar from Melilotus officinalis
- Oleanene-Type Triterpene Glycosides from Puerariae Radix. IV. Six New Saponins from Pueraria lobata
- Oleanene-Type Triterpene Glycosides from Puerariae Radix. III.Three New Saponins from Pueraria thomsonii
- Antinociceptive Activities of α-Truxillic Acid and β-Truxinic Acid Derivatives(Pharmacognosy)
- Anti-inflammatory Activity of 4,4'-Dihydroxy-α-truxillic Acid(Pharmacognosy)
- Quantitative Determination of Incarvillateine in Incarvillea sinensis by Solid Phase Extraction and High Performance Liquid Chromatography
- Anti-inflammatory Activities of α-Truxillic Acid Derivatives and Their Monomer Components(Medicinal Chemistry)
- A Monoterpene Alkaloid from Incarvillea sinensis
- Two Novel Actinidine-Type Monoterpene Alkaloids from Incarvillea delavayi
- Five New Monoterpene Glycosides and Other Compounds form Foeniculi Fructus (Fruit of Foeniculum vulgare MILLER)
- Studies on the Constituents of Gueldenstaedtia multiflora
- Three New Monoterpenoids from the Fruit of Genipa americana
- Four New Triterpene Glycosides from Nigella damascena
- New Iridoid Glucosides from the Aerial Parts of Verbena brasiliensis
- ウスバサイシンAsiasarum sieboldii F. Maekawaの発芽特性
- New Bisabolane-Type Sesquiterpenes from the Aerial Parts of Lippia dulcis
- Examination for Estrogenic Activities of Soyasaponin I and Related Compounds
- A New Lignan Glycoside and Phenylethanoid Glycosides from Strobilanthes cusia BREMEK
- Soy Isoflavone Metabolites Isolated from Human Urine
- Pregnane- and Furostane-Type Oligoglycosides from the Seeds of Allium tuberosum
- Steroids from the Underground Parts of Trillium kamtschaticum
- Hepatoprotective Constituents in Plants 14. Effects of Soyasapogenol B, Sophoradiol, and Their Glucuronides on the Cytotoxicity of tert-Butyl Hydroperoxide to HepG2 Cells(Pharmacognosy)
- Four New Cycloartane Glycosides from Aquilegia vulgaris
- Sesquiterpenoids, Triterpenoids, and Flavonoids from the Fruits of Schinus molle
- DPPH radical-scavenging effect on some constituents from the aerial parts of Lippia triphylla
- Two new lignan glucosides from the fruit of Vitex cannabifolia
- Two Novel Antioxidant Ortho-Benzoyloxyphenyl Acetic Acid Derivatives from the Fruit of Vaccinium uliginosum
- Two New Steroid Glycosides and a New Sesquiterpenoid Glycoside from the Underground Parts of Trillium kamtschaticum
- Iridoid Glucosides from the Fruit of Genipa americana
- Antioxidative, Antihyaluronidase and Antityrosinase Activities of Some Constituents from the Aerial Part of Piper elongatum VAHL.
- Evaluation of the Anti-oxidative Effect (in vitro) of Tea Polyphenols(Organic Chemistry)
- A New Triterpene Glucosyl Ester from the Fruit of the Blackberry (Rubus allegheniensis)
- Antioxidant Ortho-Benzoyloxyphenyl Acetic Acid Ester, Vaccihein A, from the Fruit of Rabbiteye Blueberry (Vaccinium ashei)
- New Megastigmane Glycoside and Aromadendrane Derivative from the Aerial Part of Piper elongatum
- Antioxidative and Antihyaluronidase Activities of Some Constituents from the Aerial Part of Daucus carota
- Antioxidative Constituents from Tessaria integrifolia
- Anti-Oxidative Constituents from Leonurii Herba (Leonurus japonicus)
- Antioxidative Constituents from Viticis trifoliae Fructus (Fruit of Vitex rotundifolia L.)
- Antiproliferative Activity of Phenylpropanoid Ester Glycosides from Ligustrum purpurascens
- Cholestane Glycosides from Solanum abutiloides
- Monoterpene Alkaloids from Incarvillea sinensis. VI. Absolute Stereochemistry of Incarvilline and Structure of a New Alkaloid, Hydroxyincarvilline
- A New Lupane Glycoside from the Leaves of Acanthopanax koreanum
- Lupane-Triterpene Glycosides from the Leaves of Acanthopanax gracilistylus
- Metabolism of Chiisanoside from Acanthopanax divaricatus var.albeofructus by Human Intestinal Bacteria and Its Relation to Some Biological Activities
- Two 3,4-seco-Lupane Triterpenes from Leaves of Acanthopanax divaricatus var. albeofructus
- Two New Lupane-Triterpene Glycosides from Leaves of Acanthopanax koreanum
- Flavonoid Glycosides and Cardiac Glycoside from Erysimum cheiranthoides
- Cardiac Glycosides form Erysimum cheiranthoides
- Furostanol Glycosides from Asparagus mairei
- Studies of the chemical constituents of the flower buds of Magnolia kobus and M. salicifolia
- Partial Hydrolysis of Soyasaponin I and the Hepatoprotective Effects of the Hydrolytic Products. Study of the Structure-Hepatoprotective Relationship of Soyasapogenol B Analogs
- Three New Acyclic Diterpene Glycosides from the Aerial Parts of Paprika and Pimiento
- Acyclic Diterpene Glycosides, Capsianosides C,D,E,F and III, from the Fruits of Hot Red Pepper Capsicum annuum L. Used in Kimchi and Their Revised Structures
- Studies on the chemical constituents of green leaves of Eucommia ulmoides Oliv.
- Physiological functions of solanaceous and tomato steroidal glycosides
- Acyclic Diterpene Glycosides, Capsianosides VIII, IX, X, XIII, XV and XVI from the Fruits of Paprika Capsicum annuum L. var. grossum BAILEY and Jalapeno Capsicum annuum L. var. annuum
- P-229 NEW STEROIDAL GLYCOSIDES FROM TUBOCAPSICUM ANOMALUM
- Tomato New Sapogenols : Isoesculeogenin A and Esculeogenin B
- A New Tomato Pregnane Glycoside from the Overripe Fruits
- Four Novel Withanolide-Type Steroids from the Leaves of Solanum cilistum
- Six New Withanolide-Type Steroids from the Leaves of Solanum cilistum
- Studies on the Constituents of Solanaceous Plants. (46). Steroidal Glycosides from the Fruits of Solanum anguivi
- Studies on the Constituents of Solanaceous Plants, Steroidal Glycosides from Solanum nodiflorum
- Triterpene Saponins from Abrus cantoniensis (Leguminosae). II. Characterization of Six New Saponins Having a Branched-Chain Sugar
- Triterpene Saponins from Abrus cantoniensis (Leguminosae). I. Isolatioin and Characterization of Four New Saponins and a New Sapogenol
- Antioxidative Substances in the Leaves of Ligustrum purpurascens
- Cytotoxic Activities of Solanum Steroidal Glycosides
- STUDIES ON THE CONSTITUENTS OF ABRI HERBA EFFECTIVE ON EXPERIMENTAL LIVER INJURIES
- Cardiac Glycosides from Erysimum cheiranthoides
- New Oleanene Glycosides from the Leaves of Acanthopanax japonicus
- Two Novel Dicoumaro-p-menthanes from Gerbera piloselloides (L.) CASS.
- Microbial metabolism of soy isoflavones by human intestinal bacterial strains
- Two New Cycloartane Glycosides from the Underground Parts of Aquilegia vulgaris
- A New Steroidal Glycoside and a New Phenyl Glycoside from a Ripe Cherry Tomato
- New C_ Steroidal Glycosides from Tubocapsicum anomalum
- A New Homostilbene and Two New Homoisoflavones from the Bulbs of Scilla scilloides
- Mechanism for Conversion of Spirosolane Derivative into Pregnane
- A Pregnane Glycoside from Overripe Tomato
- Two Labdane Diterpene and Megastigmane Glycosides from Aquilegia hybrida
- Conversion of Esculeoside A into Esculeogenin B
- Three New Steroid Glycosides from the Underground Parts of Trillium kamtschaticum
- Three New 15,16-Seco-cycloartane Glycosides from Cimicifuga Rhizome
- New C_ Steroidal Glycosides from Tubocapsicum anomalum
- Two New 15-Deoxycimigenol-Type and Three New 24-epi-Cimigenol-Type Glycosides from Cimicifuga Rhizome
- Steroidal Alkaloid Glycosides, Esculeosides C and D, from the Ripe Fruit of Cherry Tomato