Eosinophilic pneumonia and thoracic metastases as an initial manifestation of prostatic carcinoma

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概要

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• We herein report an 80-year-old man with prostatic carcinoma who developed eosinophilic pneumonia and intrathoracic metastases. He presented with shortness of breath, cough, and fever as a chief complaint. Chest X-ray and computed tomography showed bilateral pulmonary nodules, intrathoracic lymphadenopathy, and right-sided consolidation. Positron emission tomography (PET) using F-fluorodeoxyglucose (FDG) showed poor uptake in these nodules and lymph nodes. The patient subsequently received a pelvic computed tomography scan, which revealed a massively enlarged prostate. The serum prostate specific antigen level was elevated to 4,181.2 ng/mL, and a transrectal biopsy revealed prostatic adenocarcinoma. Based on the morphological and immunohistochemical findings, the nodules in the lung and the lymph nodes were diagnosed as secondary neoplasm from the prostate. As for right-sided consolidation, remarkable bronchoalvelar lavage fluid eosinophilia was detected that was compatible with eosinophilic pneumonia. Eosinophilic pneumonia in this case disappeared and has not recurred by treatment of prostatic carcinoma and steroid therapy for a week, and was regarded to be tumor-associated. Although prostatic carcinoma with an initial manifestation of intrathoracic metastases and eosinophilic pneumonia is uncommon, physicians should suspect the condition. In addition, we should also keep in mind that prostatic carcinoma sometimes shows poor uptake in FDG-PET. © 2008 The Japanese Society of Internal Medicine.

• 日本内科学会 = Japanese Society of Internal Medicineの論文

著者

• Yasui Masahide

  Respiratory Medicine Cellular Transplantation Biology Kanazawa University Graduate School Of Medicin

• Kimura Hideharu

  Respiratory Medicine, Kanazawa University Hospital

• Kasahara Kazuo

  Respiratory Medicine, Kanazawa University Hospital

• Kasahara K

  Respiratory Medicine Cellular Transplantation Biology Kanazawa University Graduate School Of Medicin

• FUJIMURA Masaki

  Respiratory Medicine, Cellular Transplantation Biology, Kanazawa University Graduate School of Medic

• KATAYAMA Nobuyuki

  Respiratory Medicine, Cellular Transplantation Biology, Kanazawa University Graduate School of Medic

• ARAYA Tomoyuki

  Respiratory Medicine, Cellular Transplantation Biology, Kanazawa University Graduate School of Medic

• Ishiguro Takashi

  Respiratory Medicine, Cellular Transplantation Biology, Kanazawa University Graduate School of Medic

• Minato Hiroshi

  Pathology Section, Kanazawa University Hospital

• Kimura Hideharu

  Respiratory Medicine Cellular Transplantation Biology Kanazawa University Graduate School Of Medicin

• Kasahara Kazuo

  Respiratory Medicine Cellular Transplantation Biology Kanazawa University Graduate School Of Medicin

• Araya Tomoyuki

  Respiratory Medicine Cellular Transplantation Biology Kanazawa University Graduate School Of Medicin

• Fujimura Masaki

  Respiratory Medicine Cellular Trans Plantation Biology Kanazawa Graduate University School Of Medici

• Katayama Nobuyuki

  Respiratory Medicine Cellular Transplantation Biology Kanazawa University Graduate School Of Medicin

• Minato Hiroshi

  Pathology Division Kanazawa University Hospital

• Fujimura Masaki

  Pulmonary Medicine Cellular Transplantation Biology Kanazawa Graduate School Of Medicine

• 藤村 政樹

  金沢大学大学院医学系研究科細胞移植学・呼吸器内

• Araya Tomoyuki

  Respiratory Medicine, Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science

• Kasahara Kazuo

  Respiratory Medicine, Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science

• Ishiguro Takashi

  Respiratory Medicine, Cellular Transplantation Biology, Graduate School of Medicine, Kanazawa University

• Ishiguro Takashi

  Respiratory Medicine, Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science

• Yasui Masahide

  Respiratory Medicine, Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science

• Kimura Hideharu

  Respiratory Medicine, Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science

• Katayama Nobuyuki

  Respiratory Medicine, Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science

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