Feasibility of eradication of mutans streptococci from oral cavities
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概要
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Objectives: Dental caries prevention programs using chlorhexidine (CHX) have been proposed, but CHXs effect in reducing levels of mutans streptococci (S. mutans and S. sobrinus) appears to last for only a few months. The aim of this study was to attempt to eradicate mutans streptococci from the oral cavity using intensive professional mechanical tooth cleaning (PMTC) and topical application of CHX in custom-made trays. Methods: Seven adult dentate subjects participated in this study (mean age 53.7 +/− 5.6, age range 46 to 62, mean DMFT, 9.1 +/− 4.2). For each subject, PMTC was carried out eight times within ten days. After each PMTC, 1% CHX was applied twice to the tooth surface using custom-made trays. In addition, as home treatment, subjects were required to carry out tooth brushing three times a day, and apply 0.2% CHX in custom trays after brushing in the morning and evening. In addition, subjects rinsed with 0.2% CHX solution after lunch. Salivary levels of mutans streptococci were evaluated using Dentocult-SM at baseline and on days 9, 20, 70, 120. Results: Mutans streptococci were eradicated by day 120 from 4 of the 7 seven subjects participating in this study. Those 3 subjects still harboring mutans streptococci exhibited deep periodontal pocketing. Conclusions: Eradication of mutans streptococci from the oral cavity is feasible using a combination of CHX application in custom-made trays and intensive PMTC. (J. Oral Sci. 46, 179-183, 2004)
著者
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Takeuchi Hiroaki
Department of Oral Health, National Institute of Public Health
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Hanada Nobuhiro
Department Of Oral Health National Institute Of Public Health
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Nomura Yoshiaki
Department Of Oral Health National Institute Of Public Health
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IMAI Susumu
Department of Oral Health, National Institute of Public Health
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Imai Susumu
Department Of Electronics College Of Engineering University Of Osaka Prefecture
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Kaneko Noboru
Department Of Cardiology And Pneumology Dokkyo Medical University
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Ikemi Takuji
Department Of Dental Caries Control And Aesthetic Dentistry Nihon University School Of Dentistry At
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Fukushima Kazuo
Department Of Environmental Sciences Faculty Of Science Shinshu University
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Takeuchi Hiroaki
Department Of Applied Chemistry School Of Science And Engineering Waseda University
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Matin Khairul
Department of Oral Health, National Institute of Public Health
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IKEMI Takuji
Department of Operative Dentistry, Nihon University School of Dentistry at Matsudo
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Iguchi Ritsuko
Department of Operative Dentistry, Nihon University School of Dentistry at Matsudo
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Toyoshima Yoshihiro
Dai-ichi Mutual Life Insurance Company, Hibiya Medical Center
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Kono Yoshiharu
Department of Operative Dentistry, Nihon University School of Dentistry at Matsudo
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Nishizawa Toshiki
Department of Oral Health, National Institute of Public Health
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