信州大学医学部附属病院にて検出されたStreptococcus属の抗菌薬感受性

概要

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For empiric therapy against infections, it is most important to select antibiotics on the basis of statistical analyses of drug-resistance of the bacteria isolated in a hospital or a region. In the Department of Laboratory Medicine at Shinshu University Hospital, we created a database of bacterial data by a new bacteriological examination system,and can easily obtain information about the drug resistance.In this study,we examined drug-resistance of streptococcus species isolated at Shinshu University Hospital from October 2000 to September 2002. More than a half of S. pneumoniae were resistant to penicillin, while most of S. pyogenes and S. agalactiae species were susceptible to PCG. The S. milleri group, including S. anginosus and S. constellatus, were also susceptible to PCG and clindamycin. More than a half of S.viridans, including S. mitis and S. sanguinis,were resistant to PCG. All streptococci except S. pneumoniae were susceptible to Trimethoprim / Sulfamethoxazole and vancomycin. Both antibiotics may be useful in the treatment of patients severely infected with S. viridans or unknown streptococci.
信州医学会の論文